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Mixed Connective Tissue Disease Immunology

Studies conducted at Medical University of Graz, Department of Dermatology on mixed connective tissue disease immunology recently published

Published in Immunotherapy Weekly, October 24th, 2007

Current study results from the report, 'High serum levels of antibodies against the recombinant 70 kDa ribonucleoprotein are useful for diagnosing mixed connective tissue disease,' have been published. "' Anti-Sm antibodies and anti-RNP antibodies are considered to be diagnostic markers of systemic lupus erythematosus (SLE) and mixed connective tissue disease (MCTD). However, cross-reactivity between the antibodies diminishes their discriminating specificity between these diagnoses," scientists in Graz, Austria report.

"We examined whether we could achieve better differentiation between these two disease entities using recombinant antigens to RNP70 and SmD and...

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