Published in Immunotherapy Weekly, December 5th, 2007
"The monoclonal antibody bevacizumab blocks VEGF in the blood of patients within hours after administration. Platelets are known to endocytose plasma proteins including immunoglobulins. We tested the hypothesis that platelets take up bevacizumab Fluorescence-activated cell sorting analysis, immunofluorescence imaging, and Western blotting were used to study uptake and release...
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