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Encephalomyelitis Immunology

Researchers at Harvard University, Center for Neurologic Diseases target encephalomyelitis immunology

Published in Immunotherapy Weekly, January 16th, 2008

Researchers detail in 'The dynamics of effector T cells and Foxp3+ regulatory T cells in the promotion and regulation of autoimmune encephalomyelitis,' new data in encephalomyelitis. "The Th1/Th2 paradigm of T helper cell subsets had to be revised when IL-17 producing T cells (Th17) were identified as a distinct T helper cell lineage. Th17 cells are very efficient inducers of tissue inflammation and crucial initiators of organ-specific autoimmunity," researchers in the United States report.

"Whereas Th17 cells promote autoimmune tissue inflammation, Foxp3+ regulatory T cells (T-reg) are necessary and sufficient to prevent autoimmunity throughout the life span of an...

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