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Integrase

Reports outline integrase research from University of Liverpool, Biological Sciences Division

Published in Immunotherapy Weekly, January 30th, 2008

Researchers detail in 'Identification of multiple integration sites for Stx-phage Phi24B in the Escherichia coli genome, description of a novel integrase and evidence for a functional anti-repressor,' new data in integrase. According to recent research published in the journal Microbiology, "The key virulence factor in Shiga-toxigenic Escherichia coli is the expression of Shiga toxin (Stx), which is conferred by Stx-encoding temperate lambdoid phages (Stx-phages). It had been assumed that Stx-phages would behave similarly to lambda phage."

"However, contrary to the lambda superinfection immunity model, it has been demonstrated that double lysogens can be...

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