Brucellosis
New Brucellosis research has been reported by J.H. Wyckoff et al
Published in Immunotherapy Weekly, January 30th, 2008
"The present study was an investigation into the role of T lymphocytes in the killing of antigen-sensitized macrophages (M phi) in bovine brucellosis. Following confirmation of bovine T lymphocyte cell lines derived from Brucella abortus Strain 19 vaccinated steers as antigen-specific in proliferation studies using various antigens, we adapted an apoptosis assay for evaluation of cytotoxicity by these bovine T cells against autologous monocyte-derived macrophages (MDM phi)as target cells. Various B. abortus antigen preparations were tested including whole gamma-irradiated B. abortus bacteria (gamma BA), a soluble cytosolic protein fraction and a membrane-associated protein fraction,"...
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Source: Immunotherapy Weekly (2008-01-30)
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