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Gene Therapy
Research on gene therapy reported by Z. Jiang et al
May 21st, 2008
According to recent research published in the journal Biotechnology and Bioengineering, "Sodium butyrate treatment can increase the specific productivity of recombinant proteins in mammalian Cells; however, it dramatically decreases cell growth and frequently leads to apoptosis. We have studied the responses of several Chinese hamster ovary (CHO) cells lines with different specific productivities (qP) to sodium butyrate treatment." "Cell clones with lower productivities exhibited greater enhancement from butyrate treatment than cells with higher productivities. As we observed previously in cell clone characterization (Jiang et al, 2006. Biotechnol Prog 22:...
Source: Immunotherapy Weekly (2008-05-21)
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