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Immunotherapy Weekly

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Hepatitis C Virus



Study data from St. Louis University provide new insights into hepatitis C virus



May 21st, 2008

According to recent research published in the Journal of Virology, "Hepatitis C virus (HCV) often causes a persistent infection associated with hypergammaglobulinemia, high levels of antiviral antibody and circulating immune complexes, and immune complex disease. We previously reported that only a limited neutralizing activity to vesicular stomatitis virus or HCV pseudotype is generated in animals immunized with recombinant HCV envelope proteins and chronically infected HCV patient sera."

"Interestingly, when some of these neutralizing sera were diluted into a range of concentrations below those that reduced virus plaque number, an increase in pseudotype plaque...


Source: Immunotherapy Weekly (2008-05-21)

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