Immunotherapy Weekly
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Monoclonal Antibodies
Study data from Kinki University provide new insights into monoclonal antibodies
May 21st, 2008
According to a study from Osaka, Japan, "Programmed cell death (PCD) is categorized as apoptotic, autophagic, or necrosis-like. Although the possibility that plural (two or three) death signals could be induced by a given stimulus has been reported, the precise mechanisms regulating PCD are not well understood." "Recently, we have obtained two anti-chicken transferrin receptor (TfR) monoclonal antibodies (mAbs; D18 and D19) inducing a unique cell death. Although the cell death had several features of apoptosis, autophagic and necrosis-like morphological alterations were simultaneously observed in electron microphotographs. In addition to cells with condensed chromatin...
Source: Immunotherapy Weekly (2008-05-21)
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