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Immunotherapy Weekly

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Stem Cell Research



Vrije University publishes research in stem cell research



May 21st, 2008

According to recent research published in the journal Pancreas, "Many efforts are spent in identifying stem cells in adult pancreas because these could provide a source of A cells for cell-based therapy of type 1 diabetes. Prominin-1, particularly its specific glycosylation-dependent AC133 epitope, is expressed on stem/progenitor cells of various human tissues and can be used to isolate them."

"We, therefore, examined its expression in adult human pancreas. To detect prominin-1 protein, monoclonal antibody CD133/1 (AC133 clone), which recognizes the AC133 epitope, and the alpha hE2 antiserum, which is directed against the human prominin-1 polypeptide, were used....


Source: Immunotherapy Weekly (2008-05-21)

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