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Immunotherapy Weekly

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Allergies



Research results from T. Neimertandersson and co-authors update knowledge of allergies



May 21st, 2008

According to a study from Stockholm, Sweden, "Allergen-specific immunotherapy (ASIT) is the only treatment of allergic disease that gives long-lasting relief of symptoms. However, concerns for safety and efficiency have highlighted the need for improvement of the therapy."

"We have previously suggested carbohydrate-based particles (CBPs) as a novel adjuvant and allergen carrier for ASIT. Our aim of this study was to evaluate the therapeutic potential of CBPs in ASIT, employing a mouse model for cat allergy. BALB/c mice were subcutaneously immunized with the recombinant (r) cat allergen Fel d 1 followed by intranasal challenge with cat dander extract (CDE). The...


Source: Immunotherapy Weekly (2008-05-21)

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