Immunotherapy Weekly
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Breast Cancer Therapy
Reports summarize breast cancer therapy study results from University of Oklahoma, Health Science Center
May 21st, 2008
Investigators publish new data in the report 'Identification of breast cancer peptide epitopes presented by HLA-A*0201.' "Cellular immune mechanisms detect and destroy cancerous and infected cells via the human leukocyte antigen (HLA) class I molecules that present peptides of intracellular origin on the surface of all nucleated cells. The identification of novel, tumor-specific epitopes is a critical step in the development of immunotherapeutics for breast cancer," researchers in the United States report. "To directly identify peptide epitopes unique to cancerous cells, secreted human class I HLA molecules (sHLA) were constructed by deletion of the transmembrane and...
Source: Immunotherapy Weekly (2008-05-21)
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