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Hepatitis E Virus Therapy
Researchers from Jichi Medical University discuss findings in hepatitis E virus therapy
May 21st, 2008
Investigators publish new data in the report 'Production of monoclonal antibodies against hepatitis E virus capsid protein and evaluation of their neutralizing activity in a cell culture system.' "Nine murine monoclonal antibodies (mAbs) generated against a recombinant ORF2 protein (amino acids 111-660) of a genotype 4 hepatitis E virus (HEV) strain recognized four sets of epitopes by pairwise competitive ELISA. One mAb (H6225) was able to capture HEV efficiently regardless of genotype and was tested for its ability to neutralize a genotype 3 HEV strain (JE03-1760F) in a recently developed cell culture system for HEV in a hepatocarcinoma cell line (PLC/PRF/5)," researchers in Japan...
Source: Immunotherapy Weekly (2008-05-21)
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