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Immunotherapy
Research from University of Utrecht, Utrecht Institute for Pharmaceutical Science provides new data about immunotherapy
May 21st, 2008
Researchers detail in '1alpha,25-dihydroxyvitamin D3 potentiates the beneficial effects of allergen immunotherapy in a mouse model of allergic asthma: role for IL-10 and TGF-beta,' new data in immunotherapy. According to recent research published in the Journal of Immunology, "1alpha,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), a potent inhibitor of NF-kappaB expression, can prevent the maturation of dendritic cells in vitro leading to tolerogenic dendritic cells with increased potential to induce regulatory T cells. Herein, we investigated whether the combination of allergen immunotherapy with 1,25(OH)(2)D(3) potentiates the suppressive effects of immunotherapy and whether the...
Source: Immunotherapy Weekly (2008-05-21)
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