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Immunotherapy
Study results from National Institute of Allergy and Infectious Disease broaden understanding of immunotherapy
May 21st, 2008
Current study results from the report, 'CD137 costimulation of CD8+ T cells confers resistance to suppression by virus-induced regulatory T cells,' have been published. According to recent research from the United States, "Chronic viral infections cause high levels of morbidity and mortality worldwide, making the development of effective therapies a high priority for improving human health. We have used mice infected with Friend virus as a model to study immunotherapeutic approaches to the cure of chronic retroviral infections." "In chronic Friend virus infections CD4(+) T regulatory (Treg) cells suppress CD8(+) T cell effector functions critical for virus clearance. In...
Source: Immunotherapy Weekly (2008-05-21)
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