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Immunotherapy Weekly

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Leukemia Gene Therapy



New research on leukemia gene therapy from University of California, Moores Cancer Center summarized



May 21st, 2008

Investigators publish new data in the report 'Generation of T-cell lines to autologous acute myeloid leukemia cells by competitive limiting dilution culture of acute myeloid leukemia mononuclear cells.' According to recent research published in the journal Experimental Hematology, "To develop a novel method of generating multiple autologous acute myeloid leukemia (AML) reactive T-cell lines as a step toward adoptive immunotherapy for AML. AML peripheral blood mononuclear cells (MNC), including >90% AML blasts and 1% to 3% T cells, were seeded in limiting dilution culture in which AML blasts were induced to undergo dendritic cell (DC) differentiation."

"T cells...


Source: Immunotherapy Weekly (2008-05-21)

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