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Life Sciences
Investigators at Mount Sinai School of Medicine have published new data on life sciences
May 21st, 2008
Investigators publish new data in the report 'Post-activation-mediated changes in opioid receptors detected by N-terminal antibodies.' "The majority of studies examining activity-induced conformational changes in G protein-coupled receptors have focused on transmembrane helices or intracellular regions. Relatively few studies have examined the involvement of the extracellular region in general and the N-terminal region in particular in this process," investigators in the United States report. "To begin to address this, we generated a series of antibodies to the N-terminal region of opioid receptors. Characterization of these antibodies revealed that they differentially...
Source: Immunotherapy Weekly (2008-05-21)
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