Immunotherapy Weekly
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Life Sciences
Reports from Catholic University, Institute of Microbiology highlight recent research in life sciences
May 21st, 2008
Fresh data on life sciences are presented in the report 'Monoclonal antibody fragment from combinatorial phage display library neutralizes alpha-latrotoxin activity and abolishes black widow spider venom lethality, in mice.' According to a study from Rome, Italy, "Alpha-latrotoxin (alpha-ltx), a component of the venom of black widow spiders (BWSV), binds to higher vertebrates presynaptic nerve terminals, stimulating massive neurotransmitter release. This neurotoxic protein is responsible for most of the symptoms elicited in men by the bite of black widow spider (BWS), i.e. a neurological syndrome named latrodectism." "By reasoning that targeting this single component...
Source: Immunotherapy Weekly (2008-05-21)
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