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Monoclonal Antibodies
Studies from Tokushima Bunri University, Faculty of Pharmaceutical Sciences describe new findings in monoclonal antibodies
May 21st, 2008
A report, 'Generation of mouse monoclonal antibody against (-)-epigallocatechin gallate,' is newly published data in Biological and Pharmaceutical Bulletin. "Green tea is an acknowledged cancer preventive in Japan, and the main constituent of green tea catechins is (-)-epigallocatechin gallate (EGCG). To investigate the bioavailability of EGCG in humans, we generated a monoclonal antibody against EGCG in BALB/c mice by immunizing thyroglobulin-conjugated EGCG," investigators in Tokushima, Japan report. "Out of 32 hybridoma cell lines, three hybridomas were selected by enzyme-linked immunosorbent assay (ELISA), and then determined by surface plasmon resonance...
Source: Immunotherapy Weekly (2008-05-21)
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