Vivax Malaria
Research from M. Sohail and colleagues provide new insights into vivax malaria
Published in Immunotherapy Weekly, June 18th, 2008
According to recent research from Delhi, India, "The biological significance of TNF promoter polymorphism and infectious disease association prompted us to investigate whether TNF-alpha-308 G/A and -1031 T/C promoter polymorphisms are associated with Plasmodium vivax infection, cellular TNF-alpha level and possibly with clinical symptoms by employing PCR-RFLP methods. An overall significant elevation of serum TNF-a, IL-6 content (p=0.0002, p=0.002, respectively), whereas highly significant depletion of IL-10 content (p=0.0001) was observed in vivax patients."
"In addition, TNF-a concentration in patients with and without fever were found to be significant (p=0.0001,...
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Source: Immunotherapy Weekly (2008-06-18)
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