Life Sciences
Studies from National University of Singapore, Center for Life Sciences provide new data on life sciences
Published in Immunotherapy Weekly, September 10th, 2008
Researchers detail in 'CD40L-expressing CD8 T cells prime CD8alpha(+) DC for IL-12p70 production,' new data in life sciences. "CD8alpha(+) DC are implicated as the principle DC subset for cross-presentation and cross-priming of cytotoxic CD8 T cell responses. In this study, we demonstrate another unique facet of the CD8alpha(+) DC and CD8 T cell relationship, by showing that CD8 T cells reciprocally activate CD8alpha(+) DC, but not CD8alpha(-) DC, for IL-12p70 production, the key Th1-promoting cytokine," scientists in Singapore, Singapore report.
"This effect was observed during an antigen-specific interaction between DC and activated CD8 T cells, along with secondary...
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Source: Immunotherapy Weekly (2008-09-10)
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