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Autoimmune Disease

Data from University of Saarland provide new insights into autoimmune disease

Published in Immunotherapy Weekly, October 15th, 2008

In this recently published study, investigators in Homburg, Germany conducted a study "To assess the use of visual evoked potentials (VEPs) for the in vivo detection of impaired visual function in a marmoset model of multiple sclerosis. The sensitivity of the VEP recordings was determined by comparison with magnetic resonance imaging (MRI) and histopathology."

"Baseline VEPs were recorded in six healthy marmoset monkeys in response to light-flash stimulation. Experimental autoimmune encephalomyelitis (EAE) was induced in four of the six monkeys. Clinical scores were assessed daily, and VEPs were recorded every second week. In vivo MRI and subsequent histopathology of...

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