Glioblastoma
New findings reported from Kurume University describe advances in glioblastoma
Published in Immunotherapy Weekly, October 29th, 2008
According to recent research from Fukuoka, Japan, "We recently cloned a variant form of erythropoietin-producing hepatocyte (Eph)B6, a member of the Eph receptor tyrosine kinase family. In the present study, we examined the expression of the EphB6 variant (EphB6v) in a panel of brain tumor cell lines and glioblastoma tissues and we found that EphB6v was preferentially expressed in malignant brain tumors, such as glioblastomas and anaplastic astrocytomas."
"The EphB6v has a unique 54 amino acid sequence at the C-terminal that is not found in normal EphB6. Therefore, we attempted to identify antigenic peptides unique to EphB6v for immunotherapy. The two EphB6v-derived...
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Source: Immunotherapy Weekly (2008-10-29)
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