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Immunotherapy Weekly

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Immunotherapy



Research on immunotherapy reported by scientists at Harvard University



November 26th, 2008

According to recent research from the United States, "In 1992, high-dose bolus interleukin (IL)-2 was granted Food and Drug Administration approval based on its ability to produce durable complete responses in a small number of patients with metastatic renal cell carcinoma (RCC). However, the substantial toxicity and limited efficacy that is associated with IL-2 has narrowed its application to highly selected patients treated at specialized centers."

"In recent years, the relative merits of low- and high-dose cytokine regimens have been clarified by the results of 4 randomized trials. Taken together, these studies suggest that highdose IV bolus IL-2 is Superior in terms...


Source: Immunotherapy Weekly (2008-11-26)

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