Immunotherapy Weekly
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Life Sciences
New life sciences findings from C.L. Shao and co-authors described
November 26th, 2008
According to recent research published in the journal Cellular & Molecular Immunology, "H antigen, the precursor of A and B antigens, belongs to Hh blood system in which it is the only antigen. H antigen distributes on all the human RBC surface except for Bombay phenotype and the copy number of H antigen on the surface of an adult RBC is approximately 1.7 x 10(6)." "These characteristics made H antigen the potential target molecule for the immunoassay and immunotherapy. A monoclonal antibody 2E8 against H antigen on the surface of erythrocyte had been prepared in previous work. Based on this antibody, the variable region genes of heavy and light chains (V-H and...
Source: Immunotherapy Weekly (2008-11-26)
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