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Immunotherapy Weekly

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Monoclonal Antibodies



Research on monoclonal antibodies discussed by scientists at Polytechnic University



November 26th, 2008

According to recent research from Valencia, Spain, "Enzyme-linked immunosorbent assays (ELISAs) based on monoclonal antibodies for the detection of triazole fungicides have been developed. With this aim, hapten-protein conjugates, containing the common triazole and chlorinated aromatic moieties, were prepared."

"From mice immunized with these conjugates, several monoclonal antibodies (MAbs) with the ability to sensitively bind several triazoles with different specificity were obtained. Both analyte- and class-specific ELISAs were developed. The hexaconazole-specific immunoassay can determine this fungicide with a limit of detection of 0.3 mu g/L in standard buffer. The...


Source: Immunotherapy Weekly (2008-11-26)

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