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Monoclonal Antibodies
Research from University of Bonn, Department of Physiology in the area of monoclonal antibodies published
November 26th, 2008
Fresh data on monoclonal antibodies are presented in the report 'Reduction of high background staining by heating unfixed mouse skeletal muscle tissue sections allows for detection of thermostable antigens with murine monoclonal antibodies.' "Antigen detection with indirect immunohistochemical methods is hampered by high background staining if the primary antibody is from the same species as the examined tissue. This high background can be eliminated in unfixed cryostat sections of mouse skeletal muscle by boiling sections in PBS, and several proteins including even the low abundant dystrophin protein can then be easily detected with murine monoclonal antibodies," scientists writing in the...
Source: Immunotherapy Weekly (2008-11-26)
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