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Stem Cell Research
New stem cell research from Charles University outlined
November 26th, 2008
Investigators publish new data in the report 'The stem cell marker CD133 (Prominin-1) is expressed in various human glandular epithelia.' "Human prominin-1 (CD133) is expressed by various stem and progenitor cells originating from diverse sources. In addition to stem cells, its mouse ortholog is expressed in a broad range of adult epithelial cells, where it is selectively concentrated in their apical domain," scientists in Czech Republic report. "The lack of detection of prominin-1 in adult human epithelia might be explained, at least in part, by the specificity of the widely used AC133 antibody, which recognizes an epitope that seems dependent on glycosylation. Here we...
Source: Immunotherapy Weekly (2008-11-26)
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