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Behcet Disease
Data from A. Bettencourt et al provide new insights into Behcet disease
November 26th, 2008
"Human leukocyte antigen (HLA)-B*51 is a well-known genetic factor associated with Behcet's disease (BD). To analyse the influence of HLA-B*51 and other HLA class I alleles in BD susceptibility in a Portuguese population and its association with disease severity, we studied 78 BD patients and 208 healthy controls," scientists in Oporto, Portugal report. "The patients were classified into two severity groups as described by Gul et al. As expected, a higher frequency of HLA-B*51 was found. The frequency of HLA-Cw*16 alleles was significantly higher in patients. Regarding severity, HLA-B*27 frequency was higher in the severe group compared with controls and with the mild...
Source: Immunotherapy Weekly (2008-11-26)
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