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Immunotherapy Weekly

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Ankylosing Spondylitis



Research from B. Rueda and co-researchers in the area of ankylosing spondylitis described



November 26th, 2008

According to recent research published in the journal Annals of the Rheumatic Diseases, "Recent results have shown that the IL23R gene, coding for a subunit of the interleukin-23 receptor, is strongly associated with autoimmunity. The aim of the current study was to investigate, for the first time, the possible involvement of the IL23R gene in genetic susceptibility to ankylosing spondylitis (AS)."

"We carried out a case-control association study in which 365 patients with AS and 500 blood bank donors were included. Eight single nucleotide polymorphisms (SNPs) spanning the IL23R gene were selected as genetic markers for our association study and were genotyped...


Source: Immunotherapy Weekly (2008-11-26)

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