Immunotherapy Weekly
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Colon Cancer
Recent findings from C.S. Karapetis and co-authors highlight research in colon cancer
November 26th, 2008
"Treatment with cetuximab, a monoclonal antibody directed against the epidermal growth factor receptor, improves overall and progression-free survival and preserves the quality of life in patients with colorectal cancer that has not responded to chemotherapy. The mutation status of the K-ras gene in the tumor may affect the response to cetuximab and have treatment-independent prognostic value," scientists in Australia report. "We analyzed tumor samples, obtained from 394 of 572 patients (68.9%) with colorectal cancer who were randomly assigned to receive cetuximab plus best supportive care or best supportive care alone, to look for activating mutations in exon 2 of the...
Source: Immunotherapy Weekly (2008-11-26)
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