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Immunotherapy Weekly

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Cancer



Research reports from National Institutes of Health provide new insights into cancer



June 17th, 2009

According to a study from the United States, "In vivo molecularly targeted fluorescence imaging of tumors has been proposed as a strategy for improving cancer detection and management. Activatable fluorophores, which increased their fluorescence by 10-fold after binding tumor cells, result in much higher target to background ratios than conventional fluorophores."

"We developed an in vivo targeted activatable optical imaging probe based on a fluorophore-quencher pair, bound to a targeting moiety. With this system, fluorescence is quenched by the fluorophore-quencher interaction outside cancer cells, but is activated within the target cells by dissociation of the...


Source: Immunotherapy Weekly (2009-06-17)

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