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Immunotherapy Weekly

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Arthritis



New arthritis study findings have been reported by D. Reinhold and colleagues



June 17th, 2009

According to recent research published in the journal Clinical Chemistry and Laboratory Medicine, "Dipeptidyl peptidase IV (DP IV, CD26) and DP IV-like enzymes, such as dipeptidyl peptidase II (DP II), dipeptidyl peptidase 8 (DP8), and dipeptidyl peptidase 9 (DP9), have been recognized to regulate T lymphocyte activation. Lys[Z(NO2)]-thiazolidide (LZNT) and Lys[Z(NO2)]-pyrrolidide (LZNP), non-selective inhibitors of DP IV-like activity known to target DP IV as well as DP II, DP8, and DP9, suppress T lymphocyte proliferation in vitro."

"Moreover, these inhibitors are capable of attenuating the severity of autoimmune diseases, such as experimental autoimmune...


Source: Immunotherapy Weekly (2009-06-17)

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