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Crohn Disease

Recent findings from University of Munich, Department of Medicine highlight research in Crohn disease

Published in Immunotherapy Weekly, May 26th, 2010

A report, 'Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset,' is newly published data in Plos One. "Recent studies demonstrated an association of STAT4 variants with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), indicating that multiple autoimmune diseases share common susceptibility genes. We therefore investigated the influence of STAT4 variants on the susceptibility and phenotype of inflammatory bowel diseases (IBD) in a large patient and control cohort," investigators in Munich, Germany report.

"Genomic DNA from 2704 individuals of Caucasian origin including 857...

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