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Did the end of smallpox vaccination cause the explosive spread of HIV?

Published in Immunotherapy Weekly, June 2nd, 2010

Vaccinia immunization, as given to prevent the spread of smallpox, produces a five-fold reduction in HIV replication in the laboratory. Researchers writing in the open access journal BMC Immunology suggest that the end of smallpox vaccination in the mid-20th century may have caused a loss of protection that contributed to the rapid contemporary spread of HIV.

Raymond Weinstein, a family doctor turned laboratory scientist at George Mason University, Manassas, Virginia, USA, worked with a team of researchers from George Washington University and UCLA. The researchers looked at the ability of white blood cells taken from people recently immunised with vaccinia to support...

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