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Heart Transplants

Findings from University Hospital advance knowledge in heart transplants

Published in Immunotherapy Weekly, January 12th, 2011

2011 JAN 12 -- New research, 'Reduced levels of both circulating CD4+ CD25+ CD127(low/neg) and CD4+ CD8(neg) invariant natural killer regulatory T cells in stable heart transplant recipients,' is the subject of a report. According to recent research from France, "A cross-regulation between two regulatory T cell (T(reg) ) subsets [CD4(+) CD25(+) and invariant natural killer (NK) T -iNK T] has been described to be important for allograft tolerance induction. However, few studies have evaluated these cellular subsets in stable recipients as correlates of favourable clinical outcome after heart transplantation."

"T(reg) and iNK T cell levels were assayed by...

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