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Immune System

Report Summarizes Immune System Study Findings from Justus-Liebig University

Published in Immunotherapy Weekly, June 8th, 2011

2011 JUN 8 -- Data detailed in "Leukocyte accumulation in graft blood vessels during self-limiting acute rejection of rat kidneys" have been presented. "During self-limiting acute rejection preceding chronic vasculopathy, large amounts of leukocytes, predominantly monocytes, interact with the endothelium of renal allografts. We aim to characterize them and to identify targets for functional and interventional studies," scientists in Giessen, Germany report.

"Leukocytes were harvested by vascular perfusion from Fischer 344 to Lewis renal allografts or Lewis isografts, followed by flow cytometry, quantitative RT-PCR and genome-wide transcriptional profiling....

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