Rheumatoid Arthritis

Research in the Area of Rheumatoid Arthritis Reported from Northwestern University

Published in Immunotherapy Weekly, January 11th, 2012

2012 JAN 11 -- "Despite tremendous advances in the therapy of rheumatoid arthritis (RA), there remains interest in oral agents that may off er benefits that are similar to, or better than, those of biologic therapies," researchers in Chicago, Illinois report.

"In their paper, Chang and colleagues demonstrate the effectiveness of a Bruton tyrosine kinase (Btk) inhibitor in two models of RA. Btk inhibition impacts several pathways affecting both B-cell and macrophage activation, making it a promising target in RA," wrote E.M. Ruderman and colleagues, Northwestern University.

The researchers concluded: "However, other kinase inhibitors have...

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Source: Immunotherapy Weekly (2012-01-11)

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