Allergies
Reports Summarize Allergies Study Results from Yang Ming National University
Published in Immunotherapy Weekly, February 1st, 2012
2012 FEB 1 -- "Stevens-Johnson syndrome (SJS) and its related disease, toxic epidermal necrolysis (TEN), are life-threatening drug hypersensitivities with robust immune responses to drugs. Despite the strong HLA predisposition to drug hypersensitivities, such as HLA-B*1502 to carbamazepine (CBZ)-induced SJS/TEN, it remains unknown whether particular T-cell receptors (TCRs) participate in recognition of small drug/peptide-HLA complexes," scientists in Taipei, Taiwan report.
"Using the strong HLA predisposition in patients with CBZ-induced SJS/TEN as a model, we aimed to study the use of TCR repertoire in patients with drug hypersensitivity. We enrolled...
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Source: Immunotherapy Weekly (2012-02-01)
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