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Asthma

New Asthma Research Has Been Reported by Investigators at University of Alabama

Published in Immunotherapy Weekly, April 4th, 2012

2012 APR 4 -- "It has been suggested that interleukin (IL)-10 exerts immunosuppressive effects on allergic inflammation, including asthma, mainly through inhibition of Th2 cell-mediated eosinophilic airway inflammation. In a model of experimental asthma utilizing multiple intratracheal antigen challenges in sensitized mice, IL-10 production as well as eosinophilia and neutrophilia in the lung were induced by the multiple challenges," investigators in Birmingham, Alabama report.

"In this study, we set out to reveal the cellular source of endogenously produced IL-10, and the roles of IL-10 in airway leukocyte inflammation using an anti-IL-10 receptor...

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