Published in Lab Business Week, January 12th, 2004
"We recently demonstrated that exogenous Nef triggers phenotypic and functional differentiation of immature dendritic cells (DCs)," according to M.G. Quaranta and colleagues at the Istituto Superiore di Sanita in Rome. In a subsequent study, they "investigated whether the Nef-induced DC differentiation occurs with morphological remodeling," focusing on "the interference of Nef in the signaling pathways that regulates DC maturation."
The researchers "found that...
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