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Lab Business Week

Susan Hasty, Publisher

Table of Contents . . . April 11th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Lab Business Week | Other Publications

AVI BioPharma, Inc. - Neugene maker reports quarterly loss of $0.10 per share

Alfacell Corporation - Savadelis named chief financial officer at pharmaceutical firm

American Oriental Bioengineering - Bioengineering firm expects record revenue growth, income for 2003

Aspreva Pharmaceuticals Corp. - Autoimmune disease drug maker completes raises $57 million

Avitar, Inc. - Diagnostics company announces second closing of private placement

BioRexis Pharmaceutical Corp. - Biopharmaceutical firm completes $30M series B financing

Business & Finance - Scripps Research Institute plans Florida research hospital

Chronogen, Inc. - New management appointments named at drug discovery firm

Columbia Laboratories, Inc. - Women's health pharmaceutical firm reports loss of $0.20 per share

CombinatoRx, Inc. - Biopharmaceutical firm raises $30M in third venture capital round

Corixa Corp. - Immunotherapeutics firm reports quarterly loss of $0.31 per share

Cutting Edge Information - Pharmaceutical companies spend over $900M on cholesterol drugs, study shows

Cypress Bioscience, Inc. - Biotech company approved for listing on Nasdaq

Cytogen Corporation - Oncology company reports record product revenues

Depomed, Inc. - Pharmaceutical company reports loss of $1.23 per share

Acacia Research Corporation - $5.9M contract awarded for development of biowarfare technology

Academy of Allergy, Asthma and Immunology - Study: Inhaled steroid therapy does not reduce fetal growth

Access CardioSystems - Study demonstrates efficacy of automated external defibrillator

Agencourt Bioscience Corp. - RNA, cDNA purification system introduced by genomic services company

Ambit Biosciences - Biosciences firm adds members to scientific advisory board

American Academy of Orthopaedic Surgeons - Joint function discussed at meeting

Antidepressants - Consumer group seeking ban on antidepressant sues U.S. government

Aromas Syntheses Interaction Laboratory, Nice - Ion pockets on the HCV IRES IIId domain identify targets for inhibition

Baylor Health Care System - Med-XS Solutions announces surplus medical equipment management contract

Beth Israel Deaconess Medical Center - Brain enzyme thought to regulate appetite

Biomira, Inc. - Phase II colorectal vaccine trial results updated

Breast Cancer - Prospective trial shows modest benefit of tamoxifen after adjuvant chemotherapy

Breast Cancer - Study confirms conservation surgery is safe for BRCA cancers

Breast Cancer - Survival rates same for conservation treatment or mastectomy for recurrent DCIS

CardioTech International, Inc. - Alliance partners to accelerate development of drug-eluting stent

Celsion Corp. - Milestone payments received, first patients treated with Prolieve

Clearant, Inc. - Clearant process-treated allografts reduce risk of infection, study shows

Connetics Corporation - Dermatology company completes Soriatane acquisition

Cordis Corp. - Data supports performance of CYPHER Sirolimus-eluting Coronary Stent

Curative Health Services, Inc. - Early end of waiting period clears way for acquisition of Critical Care Systems

Cytyc Corporation - Novacept to be acquired in $325M cash transaction

Cytyc Corporation - ThinPrep launched at Pacific Rim Pathology Laboratory

Daiichi Pharmaceutical Corp. - FDA approves once-daily Floxin Otic (ofloxacin otic solution)

Delcath Systems, Inc. - First patient accepted in phase III liver cancer study

Diagnostic Ultrasound Corp. - Diagnostics company establishes customer care subsidiary

Dong A Pharmacy Company, Ltd. - IDPc inhibitor has anti-diabetic effects in mice fed high-sucrose diet

Duke University Medical Center - Lipid amphotericin B formulations protect post-HSCT renal function

Dynavax Technologies Corp. - Kwok named VP, chief business officer at biotech firm

EUROPA Steering Committee - Perindopril reduces cardiovascular death and heart attack risk in diabetes study

Emory University - Many patients can reduce serious risk factors with lifestyle changes alone

Emory University - Study of twins finds possible mechanism linking depression to heart disease

EraGen Biosciences - Life science companies announce gene expression technology agreement

Faculty of Pharmacy, Barcelona - Hepatitis A peptide covalently linked to liposomes

Flamel Technologies - Biopharma company reports Q4 profit due to license- and research-revenue growth

GenVec Inc., Gaithersburg - Double-ablated adenovirus has an affinity with tumor targets

GenVec, Inc. - Vaccine development helps drive company's 25% revenue increase in 2003

Genentech, Inc. - Company announces organizational changes

General Hospital of Mexico - phe67leu mutation found in SRY gene in patient with 46,XY gonadal dysgenesis

German Federal Research Center for Nutrition - Pressure treatment reduces infectivity of prions

GlaxoSmithKline KK - Novel benzophenones show promise as anti-HIV NNRTIs

GlaxoSmithKline PLC - Pharmaceutical giant GSK launches ad campaign to address gripes on drug prices

Guidant Corp. - Stent trials demonstrate positive outcomes in high-risk patients

Hamamatsu University - Surgical resection for pT2 gallbladder carcinomas yields good 5-year survival

Hannover Medical School - Beta-blocker treatment feasible for many asthma, COPD patients

Harvard University - Mixed hematopoietic chimerism cures type 1 diabetes

Harvard University - P-selectin plays key role in pathogenesis

Health Technology Center - Aging baby boomers, maturing technology will shock cardiovascular care services

Hi-Tech Pharmacal Co., Inc., - Pharmaceutical company reports 12% net income increase for the quarter

Hokkaido University - Cells expressing herpesvirus entry mediator C are resistant to pseudorabies

Homerton Hospital, London - Alternative medicines can pose risks for cancer patients

Human Genome Sciences, Inc. - LymphoStat-B selected for FDA's Pilot 2 Program

Hythiam, Inc. - Michel A. Sucher, MD, named VP clinical affairs of addiction-treatment company

INSERM EMI-U 00.18, Angiers - Food restriction affects energy metabolism in rat liver mitochondria

Imalux Corp. - Company receives FDA clearance for OCT imaging device

Imperial College London - Two better than one where lowering blood pressure is concerned

InTouch Health, Inc. - Remote-presence company secures $6.7M series B funding led by Acacia

Inhibitex, Inc. - Company initiates enrollment in phase II trial for Aurexis

Inst. of Child Health, London - Newborn hearing screening should be available in developing countries

Interleukin Genetics, Inc. - Company reports that interleukin-1 gene variants increase risk for early CHD

Ipsogen - Diagnostic tool enables analysis of molecular characteristics of breast tumors

Jichi Medical School - D-aspartyl endopeptidase scavenges noxious racemized proteins in aging

Johns Hopkins University - "Switched-off" genes put first chink in colon cell's antitumor armor

Johns Hopkins University -  P. falciparum parasitophorous vacuole membrane protein investigated

Johns Hopkins University - Artemisinin-derived trioxane dimers have potent antimalarial/anticancer activity

Johns Hopkins University - Combo of two natural toxins may be novel treatment for blood cancer

Johns Hopkins University - Researchers identify critical link in lead-induced brain swelling

Johns Hopkins University - Self-reported hepatitis B vaccination status unreliable among drug users

Johns Hopkins University Hospital - Soluble Fas levels in CSF correlate with HIV dementia severity

Joint Replacement Inst., Los Angeles - Wear in total hip arthroplasty is estimated using surrogate variables

Karolinska Institute - Antibiotics alter the normal bacterial flora in humans

Lipid Sciences, Inc. - Bosko Djordjevic elected to board of directors

Massachusetts Institute of Technology - B cells develop and transcribe immunoglobulin despite Oct-1 deficiency

Max Planck Institute of Psychiatry - Estradiol stimulates progression factors to cause pituitary adenoma growth

Mayo Clinic - Patients over 90 years of age can undergo total knee arthroplasty

McMaster University, Hamilton - Cardioprotective effects of scavenger receptor SR-BI clarified

Medical University of South Carolina - Radiofrequency catheter ablation should be used sparingly in small children

Meir Hospital - Simvastatin given with cytotoxic drugs is advantageous in myeloma cell lines

Merix Bioscience, Inc. - Geron Corp. inks agreement for therapeutic cancer-vaccine technology

Millenia Hope, Inc. - MMH Malarex yields positive results in study vs. established antimalarial drug

National University of Colombia - Functional regions of plasmodial MAEBL protein identified

Navigant Consulting, Inc. - Prediction: Worldwide movement disorders market will reach $4 billion by 2009

Netherlands Cancer Institute - Metastases share similar genetic profile to primary breast cancer tumor

NeurogesX, Inc. - Genencor's Jean-Jacques Bienaime joins board of neuropathic pain company

Nippon Medical College - Green fluorescent protein causes mitochondria to aggregate with Bcl-2

Nutrition - FDA recommends changes to food labels

Ortho Biotech Products, L.P. - Orthovisc launched for osteoarthritis knee pain

Osaka University - Hepatocyte growth factor ameliorates perfusion without boosting tumor growth

Pennsylvania State University - System to detect Listeria monocytogenes in milk and hot dogs developed

Pfizer - Results of comparison study favor exemestane for advanced disease

Pfizer Inc - VisionConnection.org Web site receives $1.2M sponsorship

Pluristem Life Systems, Inc. - Biotechnology company announces new scientific advisor

Prescription Drug Benefits - New plans shun discounts to save money

Provectus Pharmaceuticals, Inc. - Pharmaceutical company announces new member of corporate advisory board

Quaid I Azam University - Plants of Pakistan exhibit anti-diabetes effects

Royal Brompton Hospital - Cardiac resynchronization reduces all-cause mortality risk

Royal Free Hospital - Bronchoalveolar lavage T-cell subset ratios delineate respiratory diseases

Russian Academy of Medical Science - Myeloperoxidase expression identifies acute myeloblastic leukemia variants

SAS - Healthcare provider selects program to monitor key performance indicators

Sanofi-Synthelabo - Acomplia helps study patients lose weight and quit smoking

Schering AG, Germany - Oral formulation of Fasudil improves stable angina in study patients

Scripps Research Institute - Immunization attenuates psychoactive effects of nicotine

Senetek PLC - Positive results announced for long-term study of Zeatin

Seoul National Univ. Hospital - Tumor measurement with 3-D ultrasound is affected by ultrasound focus

Somanetics Corporation - INVOS cerebral oximeter monitoring reduces permanent stroke in study

Spineology Inc. - Medical technology company names new member of board of directors

St. Jude Children's Hospital - Influenza A viruses obtained from Vero cells by reverse genetics

St. Louis University - New TB vaccine now in Phase I tests

Suburban Hospital Bethesda - Cholesterol-lowering drugs may help stroke patients get well

SurgRx - Nanotechnology developer announces round C funding and new board members

Tenet Healthcare Corp. - Tenet reports 2003 fourth quarter results

Thoratec, Inc. - Company announces a new name for point-of-care blood-analysis system

Tienta Sciences, Inc. - Proteomics start-up announces SpectRIM raman spectroscopy substrate

U.S. Centers for Disease Control & Prevention - ADA responds to study citing obesity close to being leading cause of death

U.S. Centers for Disease Control & Prevention - Lack of SARS transmission observed among public hospital workers in Vietnam

U.S. Centers for Disease Control & Prevention - Serology used to determine prevalence of infection with waterborne pathogens

U.S. National Cancer Institute - Epidermal growth factor receptor inhibitors should stall cancer growth

U.S. National Cancer Institute - Interleukin-15 enhances the antitumor efficacy of CD8+ T Cells

Univ. of California, San Francisco - One million disabled adults lack adequate help with essential needs

Univ. of California, San Francisco - Scientists show prion shape affects nature of infection

Univ. of Innsbruck Hospital - CDH1 and CDH13 methylation is a marker for more aggressive cervical cancer

Univ. of Minnesota - Treatment of ductal carcinoma in situ varies widely in United States

Univ. of Texas, Dallas - Researchers describe advances in underlying causes of rare body-fat disorders

University Hospital of Zurich - Mammalian prion biology reviewed

University Hospital, Essen - Gd-DTPA safe, effective as contrast agent for MR-angiography

University at Buffalo - Fewer, but more advanced, colon cancers occur in postmenopausal women on HRT

University of Addis Ababa - Camels may be vector for multiresistant Salmonella

University of Bern - Multisegment injections give vertebroplasty an edge for treating collapse

University of Cincinnati - Reduced lipoxin linked to damaged cystic fibrosis lungs

University of Complutense - Lead and cadmium cancel each other out in perinatal study models

University of Illinois - Obese children less physically fit

University of Illinois - Rats exposed to both PCBs and methylmercury in utero experience neurotoxicity

University of Kuopio - No insulin response within 4.0-kb region of human hexokinase II promoter

University of Lancaster - Parents of young adults with cancer need to interact with health professionals

University of Leuven - Tissue donation should balance patients' rights and researchers' needs

University of Liverpool - Chemotherapy offers hope for pancreatic cancer patients

University of Lund Hospital - Autologous MDS cells can reconstitute erythrocyte populations after DLI

University of Maryland - High-mannose-type oligosaccharides bind to human antibody 2G12

University of Med. & Dentistry of New Jersey - Novel murine model better represents lung immune activity during acute TB

University of Naples Federico II - Older age at acquisition makes viral hepatitis progress faster

University of North Carolina - Bacteria manipulate Rho to enhance their survival

University of Pennsylvania - Failure of DNA repair mechanism precedes final stage of deadly leukemia

University of Regensburg - The tyrosine kinase inhibitor PTK787/ZK222584 staunches thyroid cancer growth

University of Tokyo - Hapten-specific chimeras distinguish modified cell populations

University of Tubingen - Endoglin is highly expressed in eyes with choroidal neovascularization

University of Ulsan - Sphingosine has cytotoxic effects on growth of keloid fibroblasts

University of Vienna - A 2'-succinyl linker provides oligonucleotides new conduits for conjugation

University of Virginia - FAK-Src signaling regulates adhesion disassembly

University of Zurich Hospital - Valaciclovir treats chronic hepatitis B after lung transplantation

Valle de Hebron University Hospital - Effects of gap junction signaling during myocardial ischemia-reperfusion reviewed

Vanderbilt University - Rifamycin resistance risk similar for rifampin and rifabutin DOT regimens

VaxGen - U.S. to stockpile new vaccine

Victor Babes Univ. of Medicine & Pharmacy - Veins of the human female gynecological system behave like a venous pool

Viragen, Inc. - Biotechnology names new president and chief executive officer

Virginia Commonwealth University - Impaired sense of smell increases risk for certain hazards

Wake Forest University - New findings on nerve cell proteins show promise for reducing disability

Walter Reed Army Institute of Research - Routine resistance testing can improve ART outcome in experienced patients

Washington University - Unsuspected brain region involved in side effects of diabetes drug

Wistar Institute - Research aims to create lung cancer blood tests

Wistar Institute of Anatomy & Biology - CpG methylation of plasmid vectors circumvents immune response activation

World Health Organization - Drug-resistant TB levels 10 times higher in Eastern Europe and Central Asia

Yale University - Hudson licenses radiosensitizer IPdR

Zhejiang University - Pluronic lends a hand to cationic liposomes bearing antisense oligonucleotides

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