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Lab Business Week

Susan Hasty, Publisher

Table of Contents . . . April 25th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Lab Business Week | Other Publications

A&G Pharmaceutical, Inc. - Theranostics company completes $750,000 private financing

Access Pharmaceuticals, Inc. - Pharmaceuticals company reports quarterly loss of $0.19 per share

Alltracel Pharmaceuticals Plc - Logica finance executive appointed as head of alliances, acquisitions

Amarin Corporation plc - Neuroscience pharmaceutical firm reports 4Q loss of $0.25 per share

Anadys Pharmaceuticals, Inc. - Hepatitis drug developer announces initial public offering

Ariad Pharmaceuticals, Inc. - Pharmaceutical firm announces pricing of common stock offering

AspenBio, Inc. - Hepler appointed to board of directors at biotech firm

Biovail Corporation - Pharmaceutical company renews revolving term credit facility

Bone Care International, Inc. - Pharmaceutical company files statement for common stock offering

Business & Finance - Three U.S. health plans to implement InformedRx pharmacy benefits services

Calypte Biomedical Corporation - HIV test developer reports loss of $0.04 per share

Cardima, Inc. - Cardiac device maker reports a $1.1M expense adjustment

Cellegy Pharmaceuticals, Inc. - Pharmaceutical company reports loss of $0.68 per share

Cubist Pharmaceuticals, Inc. - Revenue guidance of $40-50M given for skin disorders drug Cubicin

Cygnus, Inc. - Glucose monitor maker reports income of $1.01 per share

AVI BioPharma, Inc. - Neugene maker announces additions to board of directors

Abortion Ban - Court battle over federal abortion law begins in three cities

Advanced Nutraceuticals, Inc. - Nutraceuticals company announces sale of subsidiary

Albany Molecular Research, Inc. - Chemistry services firm announces restructuring of research departments

Allergy Medicine - Impact of asthma major focus for AAAAI in 2004

Allergy Medicine - Study: Food allergies now believed to affect 1 in 25 Americans

Altana AG - Clinical data reported on Alvesco and on its intranasal formulation

AmeriPath, Inc. - Cancer diagnostics firm announces Donald Steen as new chairman

Applied Imaging Corp. - FDA clears to market breast cancer assessment applications

Aradigm Corporation - Financial executive named to board of directors at drug delivery firm

Asahikawa Medical College - Omniflex modular hip implant system has disappointing results

Asthma - pH of exhaled breath condensate can predict asthma exacerbations in children

AtheroGenics, Inc. - Pharmaceutical company names Ryan as VP of regulatory affairs

Belgian Institute of Tropical Medicine - Assays with extended incubation phases needed to monitor HIV vaccine trials

Beth Israel Deaconess Medical Center - Thrombospondin-1 predicts how tumors respond to low-dose cyclophosphamide

Biogen Idec - Antegren to be submitted for regulatory review in Europe

Biolog, Inc. - Additional patent granted on Phenotype MicroArray technology

Boston University - Hypomethylated CpG dsDNA activates autoreactive B cells

Breast Cancer - Many women covered by Medicare are not having mammograms

Business Update - Embrex opens biotech plant in Scotland County

CHU Center-Ville, Leige - Reduced procollagen N-terminal propeptide I marks raloxifene's efficacy

Cancer Fraud - Woman says she faked daughter's cancer to keep husband from leaving

Carcinogenesis - Prenatal exposure to combustion-related pollutants damages DNA

Catholic University of Daegu - Safflower phenolic compounds improve lipid profiles

Celal Bayar University - CD4+ and HLA-DR+ T cells reduced in vitiligo patients

Chiba University - Aeration augments Aspergillus fumigatus gliotoxin production in vitro

Children's Hospital Los Angeles - National trial to study best treatment of type 2 diabetes in youth

Chinese Academy of Medical Sciences - IL-18 increases invasiveness of myeloid leukemia cells via MMP-9 upregulation

Chinese University of Hong Kong - Tissue responses to SARS-CoV vary by organ

Cleveland Clinic - Improved treatments needed to prevent restenting in diabetic patients

Cold Spring Harbor Laboratory - New RNA libraries can inactivate human genes selectively

Curie Institute - New tumor marker discovered

CytRx Corporation - FDA accepts IND for unique HIV vaccine

Dante Pazzanese Cardiology Inst., Sao Paulo - The Amplatzer device is used to close ventricular septal defects

Draximage, Inc. - Distribution agreement signed for imaging products

Dresden Univ. of Tech. - FDG-PET imaging should be used in staging early-stage Hodgkin lymphoma

EResearch Technology Inc. - Definitive Phase 1 QT ECG trial required for drug safety assessment

Emory University - Babies can get hearts with wrong blood

Federal University of Rio de Janeiro - Prevalence of HIV resistance mutations in Brazil determined

Firat University - Lipid peroxidation increased in patients with ankylosing spondylitis

Fourth Military Medical Univ., Xian - Large soft tissue defects can be repaired with thoracoumbilical flaps

Fox Chase Cancer Center - Smoking induces overexpression of estradiol-activating gene

Gene Logic, Inc - Company launches integrated toxicology outsourcing service

Genzyme Corp. - Company reports financial impact of U.K. judicial decision

Georgetown University - Altered Rho GTPase signaling pathways potential target for breast cancer therapy

GlaxoSmithKline - Diet trends may have broadened demographics of fiber market

GlaxoSmithKline - Perennial nonallergic rhinitis sufferers unaware of condition, study shows

Greystone Associates - Consulting firm reports that transdermal drug delivery continues to grow

HDC Corp. - FDA approves Neuro-Trace III neuromuscular transmission monitor

HIV/AIDS - Efforts to get AIDS medications to developing countries may be near breakthrough

HIV/AIDS - South Carolina gets $19 million for AIDS research and treatment

Hacettepe University - Primary neuroendocrine carcinoma found in the fallopian tube

Halsey Drug Co., Inc. - Company announces sale of Congers, New York, assets

Handong University - Herpes simplex virus thymidine kinase genes diminish nearby neuroblastoma cells

Harvard University - MUC1 transforming protein confers resistance to genotoxic anticancer agents

Health Protection Agency-Colindale - Low rate of enterococcal/staphylococcal resistance against oxazolidinone AZD2563

HearUSA, Inc. - Hearing aid company reports record $70.5 million 2003 revenues - up 23%

Heart Disease - Central Ohio hospital granted designation of Accredited Chest Pain Center

Hopital Tenon - Sentinel lymph node procedure in uterine cancers reviewed

Hospital 12 Octubre, Madrid - Bilateral adrenal metastasis from colorectal cancer should be managed surgically

Iconix Pharmaceuticals, Inc. - Company contributes drug signatures to promote biomarker research

Immucor, Inc. - Automated instrument reagent company fails to meet guidance

Incyte Corp. - Expanded roles for checkpoint kinases suggest target modification

Indian Institute of Science -  P. falciparum delta-aminolevulinic acid dehydratase characterized

Institut Gustave-Roussy - Poor responsiveness of breast cancer to chemotherapy explained by profile

Institute Gustave Roussy - Taq-generated products can give misleading information about RNA viruses

Ionian Technologies, Inc. - Biothreat detection device funding secured by public-private collaboration

Japanese Fdn. for Cancer Rsrch - Pasteurized autologous bone graft is useful in bone reconstruction

Johns Hopkins Medical Institutions - Angiogenesis gene linked to biomarkers of tumor-cell growth

Johns Hopkins University - Biology, not behavior, could explain reduced risk of HIV for circumcised men

Johns Hopkins University - Genetic mutation linked to infant lung disease

Johns Hopkins University - KSHV-encoded vIRF-3 activates transcriptional activity of cellular IRF-3/IRF-7

Joslin Diabetes Center - GFPT1 variations not linked to diabetic nephropathy

Karolinska Institutet - Revaccination with pneumococcal vaccine is effective in older adults

Kreatech Biotechnology, BV - Rapid Medical acquires TB-related patents

Lund University - Group B streptococcal protein rib and cholera toxin protect against infection

M.D. Anderson Cancer Center - Minimally invasive breast cancer treatment shows promise

MRC Dunn Human Nutrition Unit, Cambridge - The relationship between diet and cancer is evaluated in 10 European countries

Matsushita Memorial Hospital - Specific T-cell replete haploidentical SCT feasible for pediatric ALL

Mayo Clinic - Subtrochanteric femoral nonunions heal with appropriate grafting and implants

Mayo Clinic & Mayo Fdn - Breast pain as the only presenting symptom is rarely associated with cancer

McGill University - ASP/complement C3adesArg deficiency increases energy expenditure

Medical Discoveries, Inc. - Company receives preclinical report on MDI-P

Medicis Pharmaceutical Corp. - Dallas plastic surgeon among the first in the U.S. to offer Restylane

Merrimack Pharmaceuticals, Inc. - Pharmaceutical firm awarded SBIR grant for antibody development

Molecular Devices Corp. - Molecular Devices inks agreement to acquire electrophysiology company

National Institute of Health Sciences, Tokyo - "Infectivity PCR" enhances detection of replication-competent adenovirus vectors

National Shikoku Cancer Center - Second-line chemotherapy contributed to favorable outcome in gastric cancer

National University of Ireland Maynooth - Antisera-based immunoassay effective for aspergillosis diagnosis

Neogen Corp. - Food-safety company reports 29% revenue increase

New South Wales Cancer Council - Strong IgG antibody activity linked to high HHV-8 viremia

Northwestern University, Chicago - Researchers describe feasible alternative to bone-marrow donation

Obstetrics - Guidance issued on treatment of morning sickness during pregnancy

Obstetrics - More pregnant women in developing countries are getting antenatal care

Orphan Medical, Inc. - Enrollment complete for excessive daytime sleepiness trial

Osaka Medical Center - Early ligation of inferior pancreaticoduodenal artery reduces blood loss

PainCare Holdings, Inc. - Pain relief company announces intent to acquire Denver Pain Management

PharmaBrand, SA - Generex Biotechnology announces letter of intent for joint venture

Pharmacopeia, Inc. - Research collaboration extended

Possis Medical, Inc. - Medical device manufacturer completes extended share repurchase program

Prescription Drug Importation - State to plans to add more pharmacies to drug website

Psoriasis Foundation - Even a "small" amount of skin disease can negatively impact daily life

Public Health - New research on pediatric and inner-city asthma unveiled at AAAAI meeting

Quality Assurance - Prosecutors charge nurse in Pennsylvania patient's death

Registro Nacional do Cancer, Montevideo - Cigarette smoking increases risk of large cell carcinoma of lung

SARS - Vaccine shows promise in mice

SCOLR, Inc. - Biopharmaceutical company reports 2003 financial results

SGX - Drug discovery collaboration to develop novel small molecule therapeutics

STERIS Corp. - Fumigation technology inactivates chemical, biological agents in research

San Francisco General Hospital - Fitness loss caused by HIV resistance mutations may account for low viremia

Sanofi-Synthelabo Research - Alfuzosin 10 mg shows beneficial effect in patients with urinary retention

Sapir Medical Center, Kefar Sava - A nomogram of sonographic measurement of ovarian volume is presented

Scripps Research Institute - Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer

Sentigen Holding Corp. - Holding corporation reports 25% increase in 2003 revenues

Signet Laboratories, Inc. - Notice Of Allowance issues for sepsis and renal failure assay technology

St. Elisabeth, Trondheim - Desmopressin does not reduce postoperative bleeding in patients taking aspirin

St. Mary's Hospital, Seoul - Cytogenetic CE alone does not reduce post-SCT imatinib efficacy

Stanford University Medical Center - Blood-forming stem cells fail to repair heart muscle

Teva Pharmaceutical Industries Ltd. - Oxycodone Hydrochloride ER Tablets 80 mg receives FDA approval

Texas A&M University - Interleukin-6 stimulates a protein known to cause chemoresistance

TherMatrx, Inc. - Thermotherapy developer expects record second quarter results

Tokyo Medical & Dental University - Genomic alterations make cells more or less resistant to drug therapy

Tufts Univ., Boston - Short-term epidural anesthetic blockade decreases pain of interstitial cystitis

U.S. Centers for Disease Control & Prevention - No SARS transmission occurs with U.S. SARS patient

U.S. Centers for Disease Control and Prevention - Motor vehicle crashes claim more than a million lives worldwide

U.S. Food & Drug Administration - Acid exposure improves enrichment of enterohemorrhagic E. coli

U.S. Institute of Medicine - U.S. government issues public briefing on safety of dietary supplements

U.S. National Institutes of Health - Chimeric HIV/SIV provides stable trimeric HIV Env for study

Univ. Hospitals of Cleveland - Surgeons explore new treatment for movement disorder

Univ. of California, Los Angeles - PPAR-gamma role in cardiovascular disease reviewed

Univ. of California, Riverside - Why passive smoking hinders healing

Univ. of California, San Diego - Matrix metalloproteinase-8 plays a key role in cancer metastasis

Univ. of Illinois, Urbana-Champaign - Fatty acid pathway, glucose combine to produce triacetic acid lactone

Universite de Caen - Opioid tolerance may be a question of receptor internalization

University College London - Girls may have heightened risk of intrauterine HIV infection

University Hospital Center, Amiens - Vertebral fractures are highly prevalent among elderly French women

University Hospital, Bern - Devices that facilitate anastomoses may revolutionize coronary artery bypass

University at Buffalo - Computer-assisted cognitive rehabilitation improves drug treatment response

University at Buffalo - Vitamins C, E and grape seed extract improve smokers' response to gum treatment

University of Aachen - Lymphocyte transformation test useful to determine occupational hazards

University of Alabama - Caloric intake, body weight independently affect longevity

University of Brighton - Phosphobetaine-based copolymer coatings superior to sulfobetaine coatings

University of British Columbia - Protein tyrosine phosphatase alpha not involved in insulin signaling

University of California, Los Angeles - Pediatric brain tumors contain malignant stem cells

University of Chicago - Influence of p38 MAP kinase isoforms on erythroid differentiation determined

University of Cincinnati - New growth factor protein helps damaged hearts

University of Denver - Treatment for insulin resistance in diabetes accompanying obesity is patented

University of Goteborg - DtaP vaccine causes hypersensitivity to aluminum in children

University of Hong Kong - SARS-associated cytokine dysregulation characterized

University of Michigan - Men with family history of prostate cancer accurately predict higher risk

University of Michigan - Peritoneal fluid macrophages jumpstart endometrial inflammation

University of Michigan - Researchers involve underserved women in a cervical cancer prevention trial

University of Minnesota - Syndecan-2 is required for angiogenic sprouting in developing embryos

University of Mississippi - Endothelin-1 plays role in regulating blood pressure in obese rats

University of Nebraska - Teens who want to quit smoking need peer support

University of Ottawa - Undetectable HCV viremia and normal liver enzyme levels may not mark cure

University of Pais Vasco - Methods for HAV detection in shellfish compared

University of Pennsylvania - Driving is the biggest danger for sleepyheads

University of South Florida - Analgesic therapy may offer protection against bladder cancer

University of Tokyo - Repeat hepatectomy for recurring metastasis confers survival benefits

University of Toronto - Simplistic explanations regarding women and body image neglect other factors

University of Tubingen - Human anti-neuroblastoma antibody cloned

University of Utah - Psychometric evaluation of PSQI supports its validity but questions usefulness

University of Verona - Intravenous ibandronate is an alternative for postmenopausal osteoporosis

University of Vienna - Lactic acid bacteria and allergen induce immune response in allergy model

University of Vienna - Restenosis inhibited by tissue factor pathway inhibitor

University of Washington - Postprandial suppression of ghrelin does not predict intermeal interval

Uterine Fibroids - Uterine fibroid embolization recovery quicker than myomectomy, study shows

Via Pitagora 2-A - High risk of oro-dental problems in RDEB-HS necessitates early dental management

Washington University - Study simplifies follow-up exams for patients

Weill Cornell Medical Center - Combination of two common heart tests is strong predictor of death in patients

World Health Organization - Role of routine polio immunization in post-certification era reviewed

Wyeth Pharmaceuticals - Pharmaceutical company announces discontinuation of operations

Yale University - Cultural intervention developed for black women with type 2 diabetes

Zhejiang University -  Ginkgo biloba extract stimulates endothelial progenitor cells

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