Susan Hasty, Publisher
Table of Contents . . . April 25th, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Lab Business Week | Other Publications
A&G Pharmaceutical, Inc. - Theranostics company completes $750,000 private financing
Access Pharmaceuticals, Inc. - Pharmaceuticals company reports quarterly loss of $0.19 per share
Alltracel Pharmaceuticals Plc - Logica finance executive appointed as head of alliances, acquisitions
Amarin Corporation plc - Neuroscience pharmaceutical firm reports 4Q loss of $0.25 per share
Anadys Pharmaceuticals, Inc. - Hepatitis drug developer announces initial public offering
Ariad Pharmaceuticals, Inc. - Pharmaceutical firm announces pricing of common stock offering
AspenBio, Inc. - Hepler appointed to board of directors at biotech firm
Biovail Corporation - Pharmaceutical company renews revolving term credit facility
Bone Care International, Inc. - Pharmaceutical company files statement for common stock offering
Business & Finance - Three U.S. health plans to implement InformedRx pharmacy benefits services
Calypte Biomedical Corporation - HIV test developer reports loss of $0.04 per share
Cardima, Inc. - Cardiac device maker reports a $1.1M expense adjustment
Cellegy Pharmaceuticals, Inc. - Pharmaceutical company reports loss of $0.68 per share
Cubist Pharmaceuticals, Inc. - Revenue guidance of $40-50M given for skin disorders drug Cubicin
Cygnus, Inc. - Glucose monitor maker reports income of $1.01 per share
AVI BioPharma, Inc. - Neugene maker announces additions to board of directors
Abortion Ban - Court battle over federal abortion law begins in three cities
Advanced Nutraceuticals, Inc. - Nutraceuticals company announces sale of subsidiary
Albany Molecular Research, Inc. - Chemistry services firm announces restructuring of research departments
Allergy Medicine - Impact of asthma major focus for AAAAI in 2004
Allergy Medicine - Study: Food allergies now believed to affect 1 in 25 Americans
Altana AG - Clinical data reported on Alvesco and on its intranasal formulation
AmeriPath, Inc. - Cancer diagnostics firm announces Donald Steen as new chairman
Applied Imaging Corp. - FDA clears to market breast cancer assessment applications
Aradigm Corporation - Financial executive named to board of directors at drug delivery firm
Asahikawa Medical College - Omniflex modular hip implant system has disappointing results
Asthma - pH of exhaled breath condensate can predict asthma exacerbations in children
AtheroGenics, Inc. - Pharmaceutical company names Ryan as VP of regulatory affairs
Belgian Institute of Tropical Medicine - Assays with extended incubation phases needed to monitor HIV vaccine trials
Beth Israel Deaconess Medical Center - Thrombospondin-1 predicts how tumors respond to low-dose cyclophosphamide
Biogen Idec - Antegren to be submitted for regulatory review in Europe
Biolog, Inc. - Additional patent granted on Phenotype MicroArray technology
Boston University - Hypomethylated CpG dsDNA activates autoreactive B cells
Breast Cancer - Many women covered by Medicare are not having mammograms
Business Update - Embrex opens biotech plant in Scotland County
CHU Center-Ville, Leige - Reduced procollagen N-terminal propeptide I marks raloxifene's efficacy
Cancer Fraud - Woman says she faked daughter's cancer to keep husband from leaving
Carcinogenesis - Prenatal exposure to combustion-related pollutants damages DNA
Catholic University of Daegu - Safflower phenolic compounds improve lipid profiles
Celal Bayar University - CD4+ and HLA-DR+ T cells reduced in vitiligo patients
Chiba University - Aeration augments Aspergillus fumigatus gliotoxin production in vitro
Children's Hospital Los Angeles - National trial to study best treatment of type 2 diabetes in youth
Chinese Academy of Medical Sciences - IL-18 increases invasiveness of myeloid leukemia cells via MMP-9 upregulation
Chinese University of Hong Kong - Tissue responses to SARS-CoV vary by organ
Cleveland Clinic - Improved treatments needed to prevent restenting in diabetic patients
Cold Spring Harbor Laboratory - New RNA libraries can inactivate human genes selectively
Curie Institute - New tumor marker discovered
CytRx Corporation - FDA accepts IND for unique HIV vaccine
Dante Pazzanese Cardiology Inst., Sao Paulo - The Amplatzer device is used to close ventricular septal defects
Draximage, Inc. - Distribution agreement signed for imaging products
Dresden Univ. of Tech. - FDG-PET imaging should be used in staging early-stage Hodgkin lymphoma
EResearch Technology Inc. - Definitive Phase 1 QT ECG trial required for drug safety assessment
Emory University - Babies can get hearts with wrong blood
Federal University of Rio de Janeiro - Prevalence of HIV resistance mutations in Brazil determined
Firat University - Lipid peroxidation increased in patients with ankylosing spondylitis
Fourth Military Medical Univ., Xian - Large soft tissue defects can be repaired with thoracoumbilical flaps
Fox Chase Cancer Center - Smoking induces overexpression of estradiol-activating gene
Gene Logic, Inc - Company launches integrated toxicology outsourcing service
Genzyme Corp. - Company reports financial impact of U.K. judicial decision
Georgetown University - Altered Rho GTPase signaling pathways potential target for breast cancer therapy
GlaxoSmithKline - Diet trends may have broadened demographics of fiber market
GlaxoSmithKline - Perennial nonallergic rhinitis sufferers unaware of condition, study shows
Greystone Associates - Consulting firm reports that transdermal drug delivery continues to grow
HDC Corp. - FDA approves Neuro-Trace III neuromuscular transmission monitor
HIV/AIDS - Efforts to get AIDS medications to developing countries may be near breakthrough
HIV/AIDS - South Carolina gets $19 million for AIDS research and treatment
Hacettepe University - Primary neuroendocrine carcinoma found in the fallopian tube
Halsey Drug Co., Inc. - Company announces sale of Congers, New York, assets
Handong University - Herpes simplex virus thymidine kinase genes diminish nearby neuroblastoma cells
Harvard University - MUC1 transforming protein confers resistance to genotoxic anticancer agents
Health Protection Agency-Colindale - Low rate of enterococcal/staphylococcal resistance against oxazolidinone AZD2563
HearUSA, Inc. - Hearing aid company reports record $70.5 million 2003 revenues - up 23%
Heart Disease - Central Ohio hospital granted designation of Accredited Chest Pain Center
Hopital Tenon - Sentinel lymph node procedure in uterine cancers reviewed
Hospital 12 Octubre, Madrid - Bilateral adrenal metastasis from colorectal cancer should be managed surgically
Iconix Pharmaceuticals, Inc. - Company contributes drug signatures to promote biomarker research
Immucor, Inc. - Automated instrument reagent company fails to meet guidance
Incyte Corp. - Expanded roles for checkpoint kinases suggest target modification
Indian Institute of Science - P. falciparum delta-aminolevulinic acid dehydratase characterized
Institut Gustave-Roussy - Poor responsiveness of breast cancer to chemotherapy explained by profile
Institute Gustave Roussy - Taq-generated products can give misleading information about RNA viruses
Ionian Technologies, Inc. - Biothreat detection device funding secured by public-private collaboration
Japanese Fdn. for Cancer Rsrch - Pasteurized autologous bone graft is useful in bone reconstruction
Johns Hopkins Medical Institutions - Angiogenesis gene linked to biomarkers of tumor-cell growth
Johns Hopkins University - Biology, not behavior, could explain reduced risk of HIV for circumcised men
Johns Hopkins University - Genetic mutation linked to infant lung disease
Johns Hopkins University - KSHV-encoded vIRF-3 activates transcriptional activity of cellular IRF-3/IRF-7
Joslin Diabetes Center - GFPT1 variations not linked to diabetic nephropathy
Karolinska Institutet - Revaccination with pneumococcal vaccine is effective in older adults
Kreatech Biotechnology, BV - Rapid Medical acquires TB-related patents
Lund University - Group B streptococcal protein rib and cholera toxin protect against infection
M.D. Anderson Cancer Center - Minimally invasive breast cancer treatment shows promise
MRC Dunn Human Nutrition Unit, Cambridge - The relationship between diet and cancer is evaluated in 10 European countries
Matsushita Memorial Hospital - Specific T-cell replete haploidentical SCT feasible for pediatric ALL
Mayo Clinic - Subtrochanteric femoral nonunions heal with appropriate grafting and implants
Mayo Clinic & Mayo Fdn - Breast pain as the only presenting symptom is rarely associated with cancer
McGill University - ASP/complement C3adesArg deficiency increases energy expenditure
Medical Discoveries, Inc. - Company receives preclinical report on MDI-P
Medicis Pharmaceutical Corp. - Dallas plastic surgeon among the first in the U.S. to offer Restylane
Merrimack Pharmaceuticals, Inc. - Pharmaceutical firm awarded SBIR grant for antibody development
Molecular Devices Corp. - Molecular Devices inks agreement to acquire electrophysiology company
National Institute of Health Sciences, Tokyo - "Infectivity PCR" enhances detection of replication-competent adenovirus vectors
National Shikoku Cancer Center - Second-line chemotherapy contributed to favorable outcome in gastric cancer
National University of Ireland Maynooth - Antisera-based immunoassay effective for aspergillosis diagnosis
Neogen Corp. - Food-safety company reports 29% revenue increase
New South Wales Cancer Council - Strong IgG antibody activity linked to high HHV-8 viremia
Northwestern University, Chicago - Researchers describe feasible alternative to bone-marrow donation
Obstetrics - Guidance issued on treatment of morning sickness during pregnancy
Obstetrics - More pregnant women in developing countries are getting antenatal care
Orphan Medical, Inc. - Enrollment complete for excessive daytime sleepiness trial
Osaka Medical Center - Early ligation of inferior pancreaticoduodenal artery reduces blood loss
PainCare Holdings, Inc. - Pain relief company announces intent to acquire Denver Pain Management
PharmaBrand, SA - Generex Biotechnology announces letter of intent for joint venture
Pharmacopeia, Inc. - Research collaboration extended
Possis Medical, Inc. - Medical device manufacturer completes extended share repurchase program
Prescription Drug Importation - State to plans to add more pharmacies to drug website
Psoriasis Foundation - Even a "small" amount of skin disease can negatively impact daily life
Public Health - New research on pediatric and inner-city asthma unveiled at AAAAI meeting
Quality Assurance - Prosecutors charge nurse in Pennsylvania patient's death
Registro Nacional do Cancer, Montevideo - Cigarette smoking increases risk of large cell carcinoma of lung
SARS - Vaccine shows promise in mice
SCOLR, Inc. - Biopharmaceutical company reports 2003 financial results
SGX - Drug discovery collaboration to develop novel small molecule therapeutics
STERIS Corp. - Fumigation technology inactivates chemical, biological agents in research
San Francisco General Hospital - Fitness loss caused by HIV resistance mutations may account for low viremia
Sanofi-Synthelabo Research - Alfuzosin 10 mg shows beneficial effect in patients with urinary retention
Sapir Medical Center, Kefar Sava - A nomogram of sonographic measurement of ovarian volume is presented
Scripps Research Institute - Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer
Sentigen Holding Corp. - Holding corporation reports 25% increase in 2003 revenues
Signet Laboratories, Inc. - Notice Of Allowance issues for sepsis and renal failure assay technology
St. Elisabeth, Trondheim - Desmopressin does not reduce postoperative bleeding in patients taking aspirin
St. Mary's Hospital, Seoul - Cytogenetic CE alone does not reduce post-SCT imatinib efficacy
Stanford University Medical Center - Blood-forming stem cells fail to repair heart muscle
Teva Pharmaceutical Industries Ltd. - Oxycodone Hydrochloride ER Tablets 80 mg receives FDA approval
Texas A&M University - Interleukin-6 stimulates a protein known to cause chemoresistance
TherMatrx, Inc. - Thermotherapy developer expects record second quarter results
Tokyo Medical & Dental University - Genomic alterations make cells more or less resistant to drug therapy
Tufts Univ., Boston - Short-term epidural anesthetic blockade decreases pain of interstitial cystitis
U.S. Centers for Disease Control & Prevention - No SARS transmission occurs with U.S. SARS patient
U.S. Centers for Disease Control and Prevention - Motor vehicle crashes claim more than a million lives worldwide
U.S. Food & Drug Administration - Acid exposure improves enrichment of enterohemorrhagic E. coli
U.S. Institute of Medicine - U.S. government issues public briefing on safety of dietary supplements
U.S. National Institutes of Health - Chimeric HIV/SIV provides stable trimeric HIV Env for study
Univ. Hospitals of Cleveland - Surgeons explore new treatment for movement disorder
Univ. of California, Los Angeles - PPAR-gamma role in cardiovascular disease reviewed
Univ. of California, Riverside - Why passive smoking hinders healing
Univ. of California, San Diego - Matrix metalloproteinase-8 plays a key role in cancer metastasis
Univ. of Illinois, Urbana-Champaign - Fatty acid pathway, glucose combine to produce triacetic acid lactone
Universite de Caen - Opioid tolerance may be a question of receptor internalization
University College London - Girls may have heightened risk of intrauterine HIV infection
University Hospital Center, Amiens - Vertebral fractures are highly prevalent among elderly French women
University Hospital, Bern - Devices that facilitate anastomoses may revolutionize coronary artery bypass
University at Buffalo - Computer-assisted cognitive rehabilitation improves drug treatment response
University at Buffalo - Vitamins C, E and grape seed extract improve smokers' response to gum treatment
University of Aachen - Lymphocyte transformation test useful to determine occupational hazards
University of Alabama - Caloric intake, body weight independently affect longevity
University of Brighton - Phosphobetaine-based copolymer coatings superior to sulfobetaine coatings
University of British Columbia - Protein tyrosine phosphatase alpha not involved in insulin signaling
University of California, Los Angeles - Pediatric brain tumors contain malignant stem cells
University of Chicago - Influence of p38 MAP kinase isoforms on erythroid differentiation determined
University of Cincinnati - New growth factor protein helps damaged hearts
University of Denver - Treatment for insulin resistance in diabetes accompanying obesity is patented
University of Goteborg - DtaP vaccine causes hypersensitivity to aluminum in children
University of Hong Kong - SARS-associated cytokine dysregulation characterized
University of Michigan - Men with family history of prostate cancer accurately predict higher risk
University of Michigan - Peritoneal fluid macrophages jumpstart endometrial inflammation
University of Michigan - Researchers involve underserved women in a cervical cancer prevention trial
University of Minnesota - Syndecan-2 is required for angiogenic sprouting in developing embryos
University of Mississippi - Endothelin-1 plays role in regulating blood pressure in obese rats
University of Nebraska - Teens who want to quit smoking need peer support
University of Ottawa - Undetectable HCV viremia and normal liver enzyme levels may not mark cure
University of Pais Vasco - Methods for HAV detection in shellfish compared
University of Pennsylvania - Driving is the biggest danger for sleepyheads
University of South Florida - Analgesic therapy may offer protection against bladder cancer
University of Tokyo - Repeat hepatectomy for recurring metastasis confers survival benefits
University of Toronto - Simplistic explanations regarding women and body image neglect other factors
University of Tubingen - Human anti-neuroblastoma antibody cloned
University of Utah - Psychometric evaluation of PSQI supports its validity but questions usefulness
University of Verona - Intravenous ibandronate is an alternative for postmenopausal osteoporosis
University of Vienna - Lactic acid bacteria and allergen induce immune response in allergy model
University of Vienna - Restenosis inhibited by tissue factor pathway inhibitor
University of Washington - Postprandial suppression of ghrelin does not predict intermeal interval
Uterine Fibroids - Uterine fibroid embolization recovery quicker than myomectomy, study shows
Via Pitagora 2-A - High risk of oro-dental problems in RDEB-HS necessitates early dental management
Washington University - Study simplifies follow-up exams for patients
Weill Cornell Medical Center - Combination of two common heart tests is strong predictor of death in patients
World Health Organization - Role of routine polio immunization in post-certification era reviewed
Wyeth Pharmaceuticals - Pharmaceutical company announces discontinuation of operations
Yale University - Cultural intervention developed for black women with type 2 diabetes
Zhejiang University - Ginkgo biloba extract stimulates endothelial progenitor cells
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