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Lab Business Week

Susan Hasty, Publisher

Table of Contents . . . July 25th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Lab Business Week | Other Publications

A.P. Pharma, Inc. - Pharmaceutical company completes common stock sale

ATS Medical, Inc. - Device firm signs definitive agreements to sell $13.1M of common stock

Abaxis, Inc. - Blood analysis systems maker to be added to Russell 2000 Index

Accumetrics, Inc. - Diagnostics company announces $13.5M financing

Aeolus Pharmaceuticals, Inc. - Incara announces 1-for-10 reverse split and name change

Alnylam Pharmaceuticals, Inc. - Pharmaceutical company appoints Patricia Allen as VP of finance

Bioject Medical Technologies, Inc. - Elan's holdings of stock clarified

Biosite Incorporated - Diagnostics maker reports new option grants

Bradley Pharmaceuticals, Inc. - Pharmaceutical company reports highlights from stockholders meeting

Finance - Rite Aid announces first quarter financial results

Finance - Vantage Oncology, Inc., raises $15 million in Series B financing

Genaera Corp. - Biopharma to join Russell 3000 and Russell 2000

Isolagen, Inc. - Cellular-therapy company completes stock offering

NuVasive, Inc. - Spine-focused company underwriters exercise over-allotment option

aaiPharma Inc. - Pharmaceutical company reports net revenue increase in first quarter 2004

AGT Biosciences Limited - Merger creates genomics-driven global biotechnology company

Alaris Medical Systems - ICU Medical announces court order in patent infringement lawsuit

American Medical Association - Medical group encouraged by signs of support for national clinical trials registry

American Psychological Association - Lack of insurance, cost cited as reasons for not seeking mental health services

Arthritis - RehabCare Group develops strategic partnership with Arthritis Foundation

Barrier Therapeutics, Inc. - Liarozole receives FDA orphan drug status

Bayer HealthCare, LLC - FDA grants clearance for two additional claims for BNP test

Baylor College of Medicine - Expression library immunization can improve vaccine antigens

Baystate Medical Center - Transdermal contraceptive system reviewed

Beaumont Hospital - Novel lipid-based cochleates drive gene uptake into mammalian cells

Bioterrorism - New reporting requirement to help fight bioterrorism

Boehringer Ingelheim - Compassionate use program expanded for Tipranavir

Boston University - ART efficacy after protease inhibitor failure better in NNRTI-naive patients

Breastfeeding - WHO says alternatives to breast milk put children at health risk

CardioTech International, Inc. - Cardiology company demands delisting from German stock exchange

Carnegie Mellon University - Imaging study reveals sex-based differences that persist as mice enter adulthood

CeMines, Inc. - Diagnostics company expands, relocates

Cell Bio-Systems, Inc. - Surgical device company begins design of commerce website

Cellomics, Inc. - Agreement signed to expand availability of high content screening

Celltech Group plc - U.S. FDA approves 12-hour Codeprex

Centocor Inc. - CNTO 95 blocks alpha(v) integrins to suppress tumors in mice

Cepheid - Human in vitro diagnostics PCR patent license executed

Cetek Corporation - Byron Long joins pharmaceutical company as director of oncology research

Children's Hospital of Philadelphia - Electronic game use is associated with childhood obesity

China Medical University - Interleukin-8 marks Helicobacter pylori status in treated ulcer patients

Chinese Ministry of Agriculture - Bird flu strain may threaten humans

Codexis - David Walshaw appointed as head of production planning at biocatalysis company

Columbia University - Ultrasonic 2-D spectrum analysis useful for ocular tumor characterization

Comprehensive Health Services - Grant will fund intervention trial for depression over job loss

Correlogic Systems, Inc. - Ovarian cancer test to advance through collaboration

Ctr. Invest. & Estudios Avanzados, Mexico City - FRET inhibition effective for measuring AS-ODN activity in vivo

Cumberland - Acetadote launched for aspirin overdose

Dana Farber Cancer Inst., Boston - EGFR mutations in lung cancer may predict sensitivity to gefitinib therapy

Diomed Holdings, Inc. - Insurance coverage for EVLT procedure reaches 80 million Americans

Dynavax Technologies Corporation - Phase II/III hepatitis B trial initiated

Ege University - Inhibin alpha shows value in differential diagnosis of ovarian neoplasia

Eli Lilly & Co. - Severe infection causes almost 10% of cancer deaths

Epoch Biosciences, Inc. - Genomics company expands patent portfolio

Erasmus University, Rotterdam - Amino acid variations in CTL epitopes can affect virus-specific CTL response

Eulji University - Long-term ovarian function maintained in woman following autologous transplant

Fujita Health University - Poor glycemic control encourages VEGF-related diabetic vascular complications

Genelabs Technologies, Inc. - Adrian Arima named vice president, general counsel of biotech company

Genmab A/S - FDA accepts HuMax-CD20 IND application for chronic lymphocytic leukemia study

Germany Institute of Human Nutrition - Method to derive dietary patterns in nutritional epidemiology developed

Gilead Sciences, Inc. - Foster City, California, company to join S&P 500 Index

GlaxoSmithKline - Neurokinin receptors are targets for treating GI disorders and pain

Griffith University - Hardiness does not help women cope with stress

HKU Pasteur Research Center, Hong Kong - SARS-CoV proteinase inhibitors may be developed from existing drugs

Harvard Medical School - MRI more accurate for detecting prenatal cleft lip and palate than sonography

Harvard University - Multivitamins during pregnancy and after birth delay AIDS symptoms in women

Harvard University - Teens living in safer neighborhoods less likely to carry concealed firearms

Hiroshima University - 16-MDCT shows promise in detecting coronary artery atherosclerosis

Hong Kong Government Laboratory - High-throughput LC-MS-MS ketamine screen developed

Hospice Care - Texas-based hospice workers complete pediatric end-of-life certificate program

Hospital General Univ. Gregorio Maranon, Madrid - HAART effects survival and surrogate markers in vertically HIV-infected children

IGI, Inc. - Microencapsulation company taps Amper, Politziner & Mattia as auditors

INFOGEN, Berlin - The Rosuvastatin GALAXY Program studies cardiovascular risk reduction

Image Systems Corp - LCD systems installed at Fairview Health Services

Imaging Diagnostic Systems, Inc. - Breast Imaging System is granted Chinese patent

ImmunoGen, Inc. - Joseph J. Villafranca, PhD, joins board of cancer-therapy company

Jikei University - Dendritic cell vaccine prevents GI tumors based on mutation

Jikei University - Some ovarian intestinal-type mucinous borderline tumors are benign

Johannes Gutenberg-Universitat Mainz - Ribosome inactivating protein isolated from Trichosanthes kirilowii

Kalorama Information - Monoclonal antibody therapies continue rapid growth in cancer market

Kanazawa Medical University, Ishikawa - The role of the interleukin-6 in cardiovascular disease is unknown

Kanazawa University - Lymphocyte subsets in chronic hepatitis B patients may trigger cancer

Kantonsspital, St. Gallen - Erythema multiforme-like reaction to adalimumab reported

Karolinska Institute - Cryo-electron tomography used to characterize individual IgG molecules

Karolinska Institute - Kringle 1-5 requires cell surface ATP synthase to stop angiogenesis

Kyung Hee University - A Paeonia lactiflora root derivative compromises angiogenic growth

LI-COR Biosciences - Odyssey System being used for imaging animal models of AD

Lab. Biopathol. Nerveuse & Musculaire, Marseille - Chromosomal deletions in frozen glioma samples aid sterotactic analysis

Lasik America - Company amends letter of intent to acquire interest in sixth dialysis center

Lincoln Medical & Mental Health Center - Evolving indications for thalidomide reported

Ludwig Maximilians University, Munich - Genetic defect may boost risk of childhood asthma from passive smoking

Lumenis, Ltd. - Laser company, Palomar agree to settlement of patent litigation

Lund University - Study: Breast-milk compound kills warts

M.D. Anderson Cancer Center - Treat the cancer, but take care to protect the heart, cancer cardiologists warn

Mayo Clinic - Prevention, and treatment of rabies reviewed

MedMira, Inc. - FDA approves new Reveal G2 Rapid HIV-1 antibody test

Medical Research Council, Cambridge - Gene guns useful for cellular delivery of lipophilic dyes

Medical Services International, Inc. - VScan maker requested to participate in major test

Medication Safety - Ann Arbor hospital selects pharmacy IV automation technology

Meikai University - Iron ions modify the cytotoxicity of hydroxyketones

Merck KGaA - Novel subcellular extraction procedure facilitates protein analysis

Microbix Biosystems, Inc. - Company moves forward with flu virus yield-enhancement technology

Minerva Inst. for Biomedical Research - ACE inhibition is an unexpected benefit of statin use

Molecular Insight Pharmaceuticals, Inc. - Polymer-peptide conjugate targets prostate cancer tumor vessels in study

Mt. Sinai School of Medicine - Cortical and subcortical GABA function may be compromised in schizophrenia

Mylan Laboratories, Inc. - Bertek's parent company declares quarterly cash dividend

National Sun Yat Sen University - Canstatin-C arrests endothelial cell-associated tumor growth

National Tokyo Hospital - Japanese investigators develop new tuberculosis test

Neurochem, Inc. - North American phase III clinical trial on Alzhemed launched

New York City Department of Health - Mass smallpox vaccination does not increase cardiac death rate

NitroMed, Inc. - Nitric Oxide-enhancing COX-2 inhibitor advanced to phase II testing

Ohio State University - Mucosal antimicrobial peptide expressed by chinchilla airway identified

Okayama University - Hyperthermia augments lipofection-mediated transduction in lung cancer cells

Okayama University - Receptor deficiency stalls the efforts of lung cancer gene therapy

Okayama University - Researchers measure coronary flow reserve after coronary interventions

Ondokuz Mayis University - Routine MRI recommended for patients with facial pain

Osaka University - CGRP down-regulates IL-2 and IFN-gamma and up-regulates IL-4 production

Pasteur Institute, Paris - Somatic antibody mutations can alter superantigenic and polyreactive binding

Pennsylvania State University - New device will allow measuring blood sugar with a wave of the arm

Perlegen Sciences - Galileo discovers new gene candidate regions in whole genome study

Pharmaceutical Care Management Association - Group seeks to block enforcement of title II of DC Access Rx act

Point Therapeutics, Inc. - Clinical trial to study Talabostat in advanced chronic lymphocytic leukemia

Polish Academy of Science - Metastatic lesions from head and neck cancers often lose chromosome Y

Prana Biotechnology Limited - Australian fellowship to support neurodegenerative disease research

Prolexys Pharmaceuticals, Inc. - Pharmaceutical company announces appointment of VP, business development

Purdue University - Mechanism underlying mature-onset obesity proposed

Quest Clinical Research - Enfuvirtide safe and effective for adult and pediatric HIV-1 infection

Regeneration Technologies Inc. - BioCleanse process offers sterilized soft tissue allografts

Regina Elena Inst. for Cancer Research, Rome - Alfa-epoietin can improve anemia in patients with gynecological cancer

Rejuvenon Corporation - Pharmaceutical development company raises $37M in Series B financing

Rice University - Biologists ID defense mechanism of leading fungal pathogen

Roswell Park Cancer Institute - DNA lesion type defines death characteristics of colon carcinoma cells

Royal Free & University College Medical School - Lipoic acid and evening primrose oil prevent diabetes-induced changes

Safety Syringes Inc. - Oral and injectable Exanta launched in Germany for prevention of VTE

Sahlgrenska University Hospital - Scientists gain new insight into factors for successful single embryo transfer

Senetek PLC - Ardana to manufacture, market Invicorp erectile dysfunction treatment in E.U.

Silpakorn University - PADRE-ASREAK peptide induces mucosal immune response to Streptococcus

St. George's Hospital Medical School - Effects of passive smoking may have been underestimated

St. Marianna University, Kanagawa - Telomerized presenescent osteoblasts are able to correct bone loss

Stanford University School of Medicine - Implantable chip may offer treatment for age-related blindness

Sun Yat-sen University - Rare point mutation found in Han population of Guangdong China

TekCel, Inc. - Sample-management systems developer acquired

Temple University - Research emphasizes value of minimally invasive surgery for complex procedures

Temple University - Sutureless technique is effective for delicate thyroidectomy

Thermogenesis Corp. - Chinese cord blood stem cell bank adopts BioArchive system

Townsend Associates, Pittsburgh - Flow-type spirometer errors that elevate test results described

Tranzyme Pharma - Collaboration to develop novel genetic controls for diagnostic assays

Tufts University - Don't blame the pyramid

U.S. Food & Drug Administration - Protozoan gene expression outcomes correlate with regulation mechanism

U.S. National Institutes of Health - Millions of Hispanics at increased risk for type 2 diabetes

United Healthcare Insurance Co. - Managed care plan offered to beneficiaries in Connecticut

Univ. Hospital of Michigan - Pain experience differs among racial, gender, and age groups

Univ. of California, Los Angeles - IL-6 mediates hypoferremia of inflammation by inducing hepcidin

Univ. of California, San Diego - On-screen smoking by movie stars leads young teens to smoke

Univ. of Saarland Clinic, Hamburg - Herv-K(HML-2) Gag/Env antibodies may indicate treatment response

Univ. of Santiago de Compostela - Cysteine prodrugs may be useful neuroprotectors in Parkinson disease treatment

Univ. of Texas Medical Branch - Utility of sentinel lymph node biopsy in breast cancer reviewed

Univ. of Texas SW Medical Center - SPARC glycoprotein regulates host tissue response to tumor growth

Univ. of Texas SW Medical Center - Spontaneously immortalized fibroblasts foster the study of neoplastic activity

University of Alabama - HLA-DRB1 and -DQB1 variants associated with HIV-1 transmission events

University of Alabama - NIH consensus panel finds gastrointestinal disease under-diagnosed

University of Arizona - Polo-like kinase 1 suppression arrests the growth of pancreatic cancer cells

University of Arizona - Questioning mothers can identify children at risk of abuse

University of California, San Francisco - BAFF dependence underlies reduced survival of autoantigen-engaged B cells

University of Cambridge - Mutation in AKT2 causes severe insulin resistance and diabetes

University of Chicago - CD43 regulation of T cell activation is through an intracellular mechanism

University of Copenhagen -  Plasmodium linked to severe childhood malaria expresses PfEMP1

University of Erlangen Nurnberg - Inflammatory diseases of the nasal sinuses can have serious complications

University of Erlangen Nurnberg - Strain and strain rate are new echo parameters of regional myocardial function

University of Ferrara - Protein kinase C isozymes modulate mitochondrial Ca2+ signals

University of Helsinki - Tissue-specific promoters ensure oncolytic viruses target cancer tissues

University of Illinois - Activity of enzyme decreased in brains of teenagers who commit suicide

University of Illinois - Isolates from Aglaia silvestris exhibit potent cytotoxicity

University of Jyvaskyla - Physical activity reduces coronary heart disease risk in childhood

University of Leicester - Space technology and dental techniques combine in new cancer detector

University of London - Novel anti-Leishmania immunotherapies show promise

University of London Kings College - Potential protective effect of HLA DQB1*06 alleles on course of HIV disease

University of Maine - Women can be considered activists in the breast cancer movement

University of Manchester - E.U. "Newmood" research investigating genetic aspects of depression

University of Manchester - Role of bacteria in arsenic poisoning examined

University of Michigan - Drug regulation reexamined from perspective of innovation policy

University of Michigan Health Systems - Diffusion tensor imaging of the brain is feasible

University of Montreal - Therapy combining cyclosporin and sirolimus causes thrombotic microangiopathy

University of Munich - Patients with inoperable tumors benefit from radiofrequency ablation

University of Pennsylvania - Bacterial protein recycling factor possible key to new class of antibiotics

University of Pittsburgh - Heart allografts from donors lacking Flt3 ligand exhibit prolonged survival time

University of Saarlandes Clinic, Hamburg - Glomus tumors of the head and neck are usually diagnosed using CT and MRI.

University of Southampton - Processing of antigens delivered as DNA vaccines reviewed

University of Stuttgart - Der1p required for degradation of proteins of endoplasmic reticulum

University of Tokushima - Sequential therapy stimulates apoptosis in human oral cancer cells

University of Tokyo - Findings on platelet-activating factor may lead to treatment strategy

University of Ulm - Antigens with stress protein-capturing domain improve immunogenicity

University of Utah - Natural selection at work in ability to taste or not taste bitter compound

University of Vermont - Pregnancy, postpartum period predispose cerebral arteries to forced dilatation

University of Verona - Study finds higher-dose ibandronate regimen effective and safe

University of Washington, Seattle -  Chlamydia pneumoniae may be an infectious risk factor for atherosclerosis

Vicuron Pharmaceuticals Inc. - Biopharmaceutical company to reduce operating expenses by more than $25M

Walter Reed Army Medical Center - Diabetes increases risk of prostate cancer

Washington University - RNA knockdown of phospholipase inhibits preadipocyte differentiation

Wayne State University, Detroit - Single chamber ventricular pacing is feasible initially in the young

West Nile Virus - West Nile virus infects four horses in California

Westmead Hospital - Association not found between CCL3-L1 absence and HIV-1 infection susceptibility

World Health Organization - Kano, Nigeria, intends to resume polio immunization campaigns

Wroclaw Medical University - Vascular endothelial growth factor levels rise in ovarian cancer patients

Yale University - Yale scientists decipher odor code

Yonsei University - TLR3 isoform cloned and characterized

Zimmer Holdings, Inc. - Tucson Orthopaedic Institute to provide surgeon training in MIS procedures

demedis, GmbH - Henry Schein completes acquisition

eResearchTechnology, Inc. - $1.2M awarded to study technology for cardiac safety monitoring

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