Published in Lab Business Week, August 22nd, 2004
"Cysteine cathepsins are involved in degradation of extracellular matrix, facilitating growth, invasion, and metastasis of tumor cells, in tumor angiogenesis, in apoptosis, and in events of inflammatory and immune responses," wrote researchers from the Jozef Stefan Institute in Ljubljana.
"In this issue of Cancer Cell [we] demonstrate [the] association of increased cathepsins activity with angiogenic vasculature and invasive fronts of carcinomas during tumorigenesis in transgenic mouse models using activity-based chemical probes and in vivo imaging,"...
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