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Adventrx Pharmaceuticals, Inc.

CoFactor results reported showing antitumor activity, lower systemic toxicity

Published in Lab Business Week, November 7th, 2004

Adventrx Pharmaceuticals, Inc., (ANX) announced the results of recent preclinical studies demonstrating enhanced antitumor activity with lower systemic toxicity in a mouse model for colorectal cancer using CoFactor, as compared to leucovorin, in combination with the chemotherapeutic agent 5-fluorouracil (5-FU).

These results suggest replacing leucovorin, the currently used adjunctive agent, with CoFactor in humans could reduce the side effects associated with using 5-FU while simultaneously improving 5-FU's antitumor activity. Results were presented at the 16th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics conference in Geneva, Switzerland on...

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