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Lab Business Week

Susan Hasty, Publisher

Table of Contents . . . November 14th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Lab Business Week | Other Publications

Biopure Corporation - Pharma firm appoints Jay B. Pieper, Kenneth Ouriel to its boards

Business & Finance - D&K Healthcare expects Q1 loss, completes acquisition of PBI

Business Update - Amgen's profit surge on strong drug sales

Cell Genesys, Inc. - Cancer vaccine maker reports loss of $0.54 per share

CoAxia, Inc. - Device company receives $17.6M in series B funding

Crucell, NV - Dutch biotech reports increased Q3 revenues

Curis, Inc. - Regeneration-focused company to raise $13.2M in registered direct offering

Elite Pharmaceuticals, Inc. - Pharmaceutical completes $4.6 million private placement

Endo Pharmaceuticals Holdings - Pain-focused pharmaceutical company reports strong Q3 results

Enzo Biochem, Inc. - Gene-identification company provides 2004 update

Finance - Additional damages awarded in technology dispute

Halozyme Therapeutics, Inc. - Enzyme-focused company announces $13.9 million private financing

ILEX Oncology Inc. - Oncology drug development company reports third quarter financial results

Illumina, Inc. - Biotech reports third quarter revenue increase of 64%

ImmuCell Corporation - Biotechnology company reports increase in product sales

ADVENTRX Pharmaceuticals, Inc. - CoFactor granted orphan drug status in the EU for pancreatic cancer

AI duPont Hospital for Children - Heme and its catabolites modulate aspects of cardiac cell function

Abiomed, Inc. - First European AB5000 patient recovers from acute fulminant myocarditis

Academic Center for Dentistry, Amsterdam - Antibody fusion protein coupled to glucose oxidase is bactericidal

Academy of Dermatology - Scars don't have to mark your skin

Accordis - Grady Health System awards Medicare billing contract

Adherex Technologies, Inc. - Oncology company names former GlaxoSmithKline executive as CSO

Aegera Therapeutics, Inc. - Biotech company establishes a clinical advisory board

Aegis - Texas-based Iasis hospitals join with Tennessee group to reduce healthcare costs

AlgoRx Pharmaceuticals, Inc. - Pharmaceutical company appoints new members to clinical team

Allergy Medicine - Cesarean section might increase allergy risk in susceptible babies

Alltracel Pharmaceuticals PLC - Deal signed to launch m-doc in Australian first aid market

Alpharma, Inc. - Court denies temporary restraining order on gabapentin capsules

Altus Pharmaceuticals, Inc. - TheraCLEC granted orphan drug designation by the EMEA

American Academy of Ophthalmology - Ophthalmology association offers tips for selecting safe toys

American Chiropractic Association - Chiropractor's group reveals top 10 back-breaking jobs

American College of Rheumatology - Arthritis patients spend twice as many healthcare dollars

American Healthways, Inc. - Blue Cross Blue Shield of Massachusetts launches renal DM programs

American Soc. of Breast Surgeons - Enrollment of MammoSite patient registry completed

American, College of Chest Physicians - Respiratory therapists twice as likely to have asthma than other therapists

Applied DNA Sciences, Inc. - DNA security company names Karin Klemm as COO

Assisted Reproduction - Egg freezing likely to become important component of ART in Italy

Astex Technology - Drug discovery company strengthens management team

AstraZeneca - Survey shows patients satisfied with Seroquel

Austin Research Institute - Dendritic cells induce immunity against blood-stage malaria

Biacore International AB - Lab instrument maker updates business, finance plan

Bioenvision - Clofarabine data presented at hematology meeting

Biolog, Inc. - NIH grant to fund development of phenotype microarray technology

Biomax Informatics AG - Bioinformatics company secures EUR 2.25M growth financing

Biovail Corporation - Douglas J.P. Squires named CEO at pharmaceutical firm

Birdlife International - "Red List" keeps track of animal populations

Bone Care International, Inc. - Pharmaceutical company names Chrys Kokino as VP of marketing

Boston Scientific Corporation - Two-year follow-up data released from Taxus IV clinical trial

Business Update - Novartis reports 21% quarterly profit rise to US$1.55

CHU Brazzaville - Inflammatory arthritis in HIV infection not a form of spondyloarthropathy

CHUM, Montreal - GIPR regulatory genes are unlikely to underlie GIP-dependent Cushing syndrome

CNRS, Paris - Structure of HIV-1 genomic RNA in gp120 gene determines a recombination hot spot

California Pharmacists Association - Health experts warn Californians about importance of immunizations

Cancer & Pregnancy - Doctors report safer ways to help cancer patients have children

Cancer Therapy - High school swimmer fights cancer into remission

Cardiac Science, Inc. - Device maker comments on 2004 third quarter revenues

Carolina Allergy and Asthma Consultants - Azelastine appears effective for patients still symptomatic after fexofenadine

Case Western Reserve University - Relaxation therapy reduces postoperative pain

Case Western Reserve University - Transgene expression endures under the right conditions

Centenary Inst. Cancer Med. & Cell Biol., Newtown - Primary T cell activation sites determine intrahepatic tolerance and immunity

Centre Hospitalier Universitaire de Montpellier - Estrogens may increase risk of familiar breast cancer

Chemical Dependency - Hythiam to offer HANDS protocols to treatment facility for chemical dependency

Children's Hospital & Medical Center, Seattle - Retroviral-mediated gene transfer corrects B-cell development in murine models

Chinese Academy of Medical Science - Melatonin has potential to treat dementia in postmenopausal women

Chiral Technologies, Inc. - Biotech firm completes new headquarters and technical center

Cholestech Corp. - Diagnostics tool maker names Jack Glenn CFO

ComPsych Corporation - Stalled hiring, sustained overwork raise employee stress levels, survey shows

Corautus Genetics, Inc. - Gene-transfer company moves to Nasdaq

Corgenix Medical Corp. - Diagnostics company announces record revenues in fiscal 2004

Cornell University - Cytoplasmic dynein mediates adenovirus microtubule binding

Cornell University - Epratuzumab exerts antitumor activity in aggressive non-Hodgkin lymphoma

Cornell University - IVF not ruled out for patients treated for borderline ovarian tumors

Coronado Industries Inc. - Clinical findings for non-invasive glaucoma treatment presented

Creighton University, Omaha - Consider magnesium to replenish low serum magnesium in MI patients

DENTSPLY International, Inc. - Oraqix, a needle-free, local dental anesthetic, is launched

DOBI Medical International, Inc. - ComfortScan maker expands board of directors

Dalhousie University - CD2-CD48 interactions promote T-cell activation by stabilizing cytokine mRNA

Dyax Corp. - Fast-track designation announced for DX-88

Dynogen Pharmaceutical Inc. - Serotonin/norepinephrine reuptake inhibitor enhances natural continence

Elsie Widdowson Laboratory - Gamma-tocopherol is potential marker for nutrition-related risk

Endocrinology - GnRH affects bone metabolism at the start of estradiol suppression in IVF

Endovasc - New subsidiary will showcase ProStent Technology

Enigma Diagnostics - Tabletop DNA test laboratory developed

Entropin, Inc. - Company: Analysis supports continued development of ENT-103

European Institute of Oncology - New developments in melanoma research reviewed

Fraunhofer Institute, Hannover - Somatic mutations in genes of cardiac cells provide a novel mechanism of disease

Free University of Brussels - HDAC inhibitors reactivate HIV-1 expression in cellular reservoirs

Fuji Photo Film Co., Ltd. - Photo film company enters nucleic acid market

Generex Biotechnology Corp. - Data presented on peptide vaccine for melanoma

Genzyme Corp. - Angiopoietins contribute to the angiogenic response to hypoxia in renal cancer

Georgetown University - Anti-PfGPI antibodies fail to prevent chronic placental malaria infections

German Research Center for Biotechnology - TGF-beta receptor signaling is critical for mucosal IgA responses

HIV/AIDS Treatment - AIDS organization says it will close down

Hiroshima University - Monoclonal antibody panel against mammalian prion protein established

Hokkaido University - OK-432 after surgery for gastric cancer did not improve survival rate

Huddinge University Hospital - Mesenchymal stem cells inhibit CD25/CD38 expression on PHA-activated lymphocytes

Hungarian Academy of Sciences - Novel assay facilitates study of nuclear migration dynamics

INSERM U561, Paris - UCP2 gene promoter polymorphism modulates lipids in diabetic patients

IRCCS Policlinico San Matteo, Pavia - Full participation minimizes parallelisms and gaps between research and care

Immunicon Corp. - Cell-focused company execs adopt rule 10b5-1 prearranged stock sales plans

Immunomedics, Inc. - Biopharmaceutical company announces new board of directors member

Indiana University - Insulin pumps effective for children with diabetes

Indiana University - Syntaxin 4 transgenic mice have enhanced insulin-related glucose uptake

Influenza - Highmark to cover FluMist vaccine during 2004-2005 flu season

Influenze Vaccine - Mothers, infants line up for flu shots

Institute Pasteur, Lyon - Real-time PCR used for rapid and specific quantitation of Nipah virus

Institute of Child Health, U.K. - Lung function reduced in low birth weight infants of white nonsmokers

Instituto Superiore di Sanita - Beauty treatments facilitate the spread of viral hepatitis in Italy

JCCM, Toledo - Trichomoniasis outbreak occurred in a woodpigeon wintering roost

Johns Hopkins University - Model is a useful tool for investigating mechanisms of arrhythmia

Johns Hopkins University - Oscillator may also be a mechanism for physiological timekeeping

Karolinska Institute - Autoimmune disease may be associated with estrogen deficiency

Karolinska Institute - Maternal smoking associated with fetal risk of childhood leukemia and lymphoma

Karolinska Institute - Women who snore have a larger progression of heart disease

Kumamoto University - Tranilast ameliorates acute lung injury in guinea pigs

La Jolla Pharmaceutical Company - Biotechnology company announces appointment of new board member

Lankenau Hosp. & Inst. for Medical Research - Propafenone has limited effect on post-CABG atrial fibrillation

Lawrence Berkeley Laboratory - Mice carry disposable DNA

Legal Issues - Florida employee resigns in wake of questions in mental health audit

Leopold Franzens University - Novel technique enables DIEP flap harvest in presence of subcostal scars

Life Sciences Investors - H&Q fund pays dividend

Lifeline Cell Technology, LLC - Embryonic stem cell technology licensed for retinal cell therapeutic research

Lundbeck - Super-selective antidepressant effective, fast acting, better tolerated

M.D. Anderson Cancer Center - Molecular imaging reveals the temporal dynamics of HIF-1 in murine tumors

MIGENIX Inc. - New phase II study of hepatitis treatment underway

Max Planck Institute - Report describes factors that contribute to the arterial remodeling process

Mayo Clinic - Effective lupus treatment with minimal side effects developed

Mayo Clinic - Ketogenic diet may be started as outpatient treatment for children with epilepsy

Merck Research Laboratories - Review highlights benefits of bisphosphonate therapy

Metabolon, Inc. - $9 Million funding round closed

Mitretek Systems, Inc. - Healthcare consulting firm announces new acquisition

Morton Grove Pharmaceuticals - FDA clears generic asthma treatment for children

Nagasaki University - Encephalitis/dengue 4 virus chimera exhibits lack of neuro-invasiveness

Nagasaki University - PAI-1, uPA, and uPAR expression linked to mesangial expansion

Nagoya City University - Viral clearance mechanisms differ between hepatitis B virus genotypes A and D

National Data Bank for Rheumatic Diseases - PPI treatment prescription levels not impacted by cox-2 therapy

National Institute of Public Health & Environment -  M. tuberculosis genotypes cause wide range of immune responses

National Research Council of Canada - Liposomes prepared from BCG possessed adjuvant activity in vivo

National Research Council of Canada - Sublethal Francisella infection causes only marginal immunity

National Taiwan University - Study confirms link between cancer and common Asian nut

Natl. Center for CV Investigation, Madrid - Regulation of lipid rafts may be important for spatial control of cell migration

Natl. Partner. to Help Preg. Smokers Quit - Adverse health effects associated with smoking during pregnancy are preventable

New Mexico State University - Multivariate statistical methods effective for phytopathological research

Northwestern Memorial Hospital - Study is looking at ways to help stroke survivors regain lost motor skills

Novo Nordisk - U.S. FDA approves prefilled, multidose, disposable growth hormone delivery system

Odyssey Thera, Inc. - Agreement expanded to assess drug compounds effects in cells

Ohio State University - Amperometric assay provides sensitive measure of cholinergic transmission

Okayama University - Gene products may promote urinary tract infection by methicillin-resistant staph

Okayama University - Long-term cyclosporin A exposure suppresses cathepsin-B/-L in gingival cells

OmniCorder Technologies, Inc. - Breast cancer imaging system delivered to Italy's National Tumor Institute

Oscient Pharmaceuticals - Positive clinical efficacy data on FACTIVE presented at meeting

Overlake Hospital - Hospitals launch Sound Heart to offer patients medical care close to home

PPOM - Preferred provider network announces new management structure

Patient Care Technology Systems - Technology systems company sponsors annual meeting of emergency physicians

PediaMed - Pediatrics pharmaceutical company appoints director, field sales

Pennsylvania State University - Stigma was predictive of modified high sexual risk in men having sex with men

Picis - University of Virginia Health System selects new critical care software

Precyse Solutions - Information technology company announces new contracts

Product Licensing - Pfizer to study pain medication Celebrex for patients at risk for heart disease

Quality Assurance - Study: Hospital quality on the rise, but varies greatly by city, hospital

Quill Medical, Inc. - Medical devices and wound closure technology companies announce alliance

Regulatory Affairs Professionals Society - Professional association helps Russia become known for healthcare research

Renal Physicians Association - Physicians association encourage nephrologists to work together

Robert Wood Johnson Medical School - Refrigerated or frozen expressed breast milk loses its antioxidant content

Roswell Park Cancer Inst. - No link between conjugated linoleic acids and disease found

Russian Academy of Science - H2 O2 used as the oxygen source by Pseudomonas and Rhodococcus

SUNY-Stony Brook - Platelet mRNA profiles characterized

Sanfaustino - Natural spring mineral water from Italy may help meet calcium requirements

Sanofi-Aventis - Pharmaceutical company, P&G form alliance to market tablets for osteoporosis

Schering AG - Betaferon associated with reduced relapse rate in study patients with early MS

Seoul National University - Pharmacokinetics of erectogenic determined in diabetic rats

Sight Savers International - Program to restore sight to one million people launched

Sigma - Companies team up to provide researchers human genomic DNA for gene regulation

Specialty Risk Services - Insurance services available for nonparticipants in state workers' comp

Spectranetics Corporation - Medical device company announces resignation of customer service executive VP

Stanford University Medical Center - California university awarded NIH grant to study hypertension drug in children

Stanford University, Palo Alto - Ambulatory ECG monitoring of silent ischemia can aid disease management

State University of Ghent - Education of women is an essential part of the rebuilding of Afghanistan

Statens Serum Institute - Culture and PCR for Bordetella detection compared

Strategic Diagnostics Inc. - Biotechnology-based company updates adoption of test method for food products

Susan G. Komen Breast Cancer Fdn. - Passage of Mammography Quality Standards Reauthorization Act of 2004 lauded

Sybron Dental Specialties, Inc. - Lighter, more esthetic orthodontic device launched by dental specialty company

TRI-AD - Slight majority of FSA participants oppose health savings accounts, survey shows

Taiwan Council of Agriculture - Surfactin-producing Bacillus subtilis rapidly detected and characterized by PCR

The Centient Biotech Investor - New biotech investment newsletter launched from San Francisco

The Quigley Corporation - Pharma company receives patent approval for arthritis treatment

Tokyo Metropolitan Institute of Medical Science - Hepatitis C virus alters the ability of dendritic cells to fight infection

Tokyo Metropolitan Institute of Neuroscience - Chemokine receptor DNA therapy prevents myocarditis-associated cardiac injury

Tokyo Metropolitan University - Newly discovered protein suggests novel tumorigenic pathway

Tokyo University of Agriculture & Technology - Three SNP genotypes in ALDH2 detected using bacterial magnetic particles

Tokyo Women's Medical University - A new hepatocyte-specific autoantibody may be linked to autoimmune hepatitis

TriPath Imaging, Inc. - Developer of liquid-based Pap test awarded 5-year contract in Liverpool U.K.

Trimedyne Inc. - Laser tested for use in outpatient procedure to treat arthritis in spinal joints

Truman State University - Female ultramarathoners are more likely to have eating disorders

Tubac Holdings, Inc. - Holdings company enters into partnership with colostrum products developer

U.S. Centers for Disease Control & Prevention - Mutations in isoniazid-resistant M. tuberculosis characterized

U.S. Food and Drug Administration - FDA releases 2004 produce safety action plan

U.S. National Institutes of Health - Cancer immunotherapy beyond current vaccines reviewed

U.S. National Institutes of Health - Lessons from DES use help researchers predict other perinatal cancer risks

U.S. National Institutes of Health - To predict outbreaks, standard assumptions must be set aside

U.S. National Institutes of Health - U.S. NIH study seeks 50,000 sisters of women with breast cancer

Umea University - Adenoviruses with alternate serotypes transduce glioma cell lines

Univ. Clinic Benjamin Franklin, Berlin - Contrast echocardiography should be considered in suspected myocardial rupture

Univ. Southern California, Los Angeles - Researchers propose a cohort mechanism that may contribute to mortality rates

Univ. of California, Berkeley - Magnetocardiography is a potential screening tool

Univ. of California, Davis - Dietary intake of saturated fats reviewed

Univ. of California, Irvine - Early life stress can inhibit development of brain-cell communication zones

Univ. of California, Los Angeles - Genetically modified bone marrow treats mucopolysaccharidosis IIIB models

Univ. of California, Los Angeles - MRI appears to have some advantages over CT for detecting bleeding in brain

Univ. of California, San Diego - Brain cell transplants correct muscle spasms after aneurysm surgery

Univ. of California, San Francisco - Lipid A of Francisella tularensis modified

Univ. of California, San Francisco - New Internet resource facilitates HIV/AIDS healthcare provider training

Univ. of Massachusetts - Stem cells have potential as a study aid for breast cancer and fetal exposure

Univ. of North Carolina - Vegetables negatively associated with breast cancer in postmenopausal women

Univ. of Southern California - Study finds no link between tamoxifen and stroke

Univ. of Texas Southwestern - Researchers uncover process for sugar-induced fat formation

University College London - Why some people see "auras" around their loved ones

University of Alabama - Apolipoprotein B-containing lipoprotein particle assembly elucidated

University of Athens - RSV-A-induced bronchiolitis is more severe than RSV-B in infants

University of California, Irvine - Report reviews mammalian strategies in response to hypoxia

University of California, Santa Barbara - Tau induces cooperative Taxol microtubule binding

University of Cordoba - Imperatorin inhibits HIV-1 replication through Sp1-dependent pathway

University of Glasgow - Novel inhibitors of trypanosomal 6-phosphogluconate dehydrogenase designed

University of Heidelberg - Iron overload characterized in beta 2-microglobulin-deficient mice

University of Helsinki - Researchers develop method for detecting lignans in human plasma

University of Hong Kong - SARS coronavirus isolates susceptible to selected antiviral compounds

University of Illinois, Chicago - Risk of peripheral neuropathy associated with statin appears to be minimal

University of Iowa - IL-6 levels mediated relationship between religious attendance and mortality

University of Leicester - Evidence lacking for concomitant use of hydroxyurea plus radiotherapy

University of Maryland - Abrogation of recurrent autoimmunity provides islet graft survival

University of Maryland - ZapA functions in peptide proteolysis associated with immune response

University of Massachusetts - Use of bacteria-killing vs. bacteria-inhibiting drugs in treating infections

University of Michigan - Biosynthetic pathway and gene cluster of curacin A analyzed

University of Nijmegen - Study reports positive correlation between allopregnanolone and PBR density

University of North Carolina - Discovery might improve design, effectiveness of anticancer drugs

University of Oxford - The interleukin 1 gene cluster is involved in ankylosing spondylitis

University of Pittsburgh - Alpha-type-1 polarized dendritic cells optimize CTL-inducing activity

University of Pittsburgh - Chronic infections cause 30 million missed work days each year

University of Pompeu Fabra - Human-specific loci contribute to the risk for neurodegenerative diseases

University of Southern California - Occupational therapists study ways to prevent pressure sores

University of Szeged - Microvascular circulation plays key role in peripheral lung stability

University of Tasmania - Girls given hormones to suppress height may later have fertility problems

University of Texas - Novel protein capture approach presented

University of Tokyo - Formation of cardiac hypertrophy is regulated by positive and negative factors

University of Tokyo - NALT- versus Peyer's-patch-mediated mucosal immunity reviewed

University of Tokyo - Segment VIII preservation can reduce donor congestion

University of Toronto - Antimicrobial susceptibility of Streptococcus isolates reported

University of Toronto - Best regimen for low-risk gestational trophoblastic neoplasia remains elusive

University of Trieste - Collagen fibril patterns compared in different hybrid bonding systems

University of Turin - Intracellular Rho GTPase levels shift during hippocampal neuron development

University of Utrecht - Integrons play minor roles in antibiotic resistance in surgical units

University of Vermont - Protein C system defect may be linked to placental MPFD

University of Vienna - Marker studied in positron emission tomography imaging of adrenal masses

University of Virginia - Role of NDP kinase in cilia development elucidated

University of Washington - Rate of twin pregnancy far lower with single blastocyst transfer

University of Wollongong -  Streblus asper volatile oil has anti-leukemia activity

Valeant Pharmaceuticals - Specialty pharmaceuticals company partners to market skin care products

Vancouver General Hospital - Immunohistochemical markers in NSCLC subgroups identified

Varian Medical Systems - Experts detail how they are using Dynamic Targeting IGRT technologies

Varian, Inc. - Imaging device company acquires magnet producer Magnex Scientific Ltd.

VaxInnate Corporation - Vaccine developer receives U.S. HHS contract and grant to study innate immunity

Venetec International, Inc. - Catheter devices maker named to San Diego area Technology Fast 50 Program

Vical Incorporate - Jill M. Church appointed as chief financial officer by biopharm research company

Vision Service Plan - Sight for Students honors 250,000th recipient with free eye exam, eyeglasses

Vista Staffing Solutions, Inc. - Temporary physician staffing firms launches international services division

Wake Forest University - Soy probably doesn't affect fertility, according to research in monkeys

Wake Forest University Baptist - Screenings vital to reduce stroke rate

Walter Reed Army Institute of Research - Acute and delayed ischemia-induced gene expression characterized in rats

Washington University - Patient personality predicts preference for relationships with doctors

Wayne State University - Bacterial resistance in the U.S. increasing

Wayne State University - WHI data show benefits of oral contraceptives, risks of infertility

Wizzard Software - Parrot Software Licenses text-to-speech technology for rehabilitation programs

World Health Organization - Indoor air pollution - the killer in the kitchen

World Heart Corporation - CMS reimbursement for Novacor LVAS increased

Yale University - Psammoma bodies in cervicovaginal smears require investigation

Yamanouchi Pharmaceutical Co. Ltd. - Incadronate attenuates corticosteroid-induced osteopenia in rats

Yonsei University - Carbohydrate arrays developed

Yonsei University - Overexpression of fatty acid-binding protein related to skin aging

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