Rizzoli Orthopedic Institutes
New polymers deliver proangiogenic drugs without initiating inflammation
Published in Lab Business Week, January 16th, 2005
"The use of biodegradable polymers for drug delivery systems excluded the need for a second operation to remove the carrier. However, the development of an avascular fibrous capsule, reducing drug release, has raised concern about these polymers in terms of tissue-implant reaction. Five novel polymers were evaluated in vivo after implantation in the rat dorsal subcutis and compared to the reference polycaprolactone (PCL)," scientists in Italy report.
"Poly(cyclohexyl-sebacate) (PCS), poly (L-lactide-b-1,5-dioxepan-2-one-b-L-lactide) (PLLA-PDXO-PLLA), two...
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Source: Lab Business Week (2005-01-16)
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