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Lab Business Week

Susan Hasty, Publisher

Table of Contents . . . January 23rd, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Lab Business Week | Other Publications

Abbott - Pharmaceutical firm announces 2005 sales, earnings guidance

Abgenix, Inc. - Biotech firm prices public offering of convertible senior notes

Aceto Corporation - Pharmaceuticals distributor reports 30% increase in stock dividend

Adeza Biomedical Corporation - Women's health product maker announces IPO

Apotex, Inc. - $2M donated to faculty of pharmacy at University of Toronto

Array BioPharma, Inc. - Biopharmaceutical firm exercises over-allotment option, completes offering

Arryx, Inc. - Nano-device maker closes on $10M financing

Avitar, Inc. - Diagnostics company announces $1,285,000 private placement

BioForce Nanosciences, Inc. - Nanotechnology firm completes key funding round

Bioject Medical Technologies, Inc. - Drug delivery company receives milestone payment from Merial

Biomet, Inc. - Device firm reports 18% increase in net sales

Biopure Corporation - Pharmaceutical firm raises $11.6M through sale of common stock, warrants

Business and Finance - DrugMax, Inc., to be listed again under "DMAX" ticker symbol

CryoLife, Inc. - Implantable tissue company files shelf registration statement

Cubist Pharmaceuticals, Inc. - Cubicin maker pays in full $29 million of convertible bond debt

!University of Paris - Class of myopathies is produced by abnormal desmin

AIdentity Matrix - Imaging center implements technology solution to decrease medical mistakes

Academia Sinica - Fusion core of SARS-coronavirus spike protein characterized

Active Biotech - Clinical studies commence in prostate cancer patients

Advancis Pharmaceutical Corporation - Pharmaceutical firm modifies Amoxicillin Pulsys agreement

Aging - Study data suggest Ink4a/Arf expression is a biomarker of mammalian aging

Allen Institute for Brain Science - First major data released from Brain Atlas

Alliance Medical Corporation - FDA clearance granted for diamond drill burs

American Legacy Foundation - CEO of foundation dedicated to smoke-free world comments on secondhand smoke

American Lung Association of Sacramento-Emigrant T - California-based lung association web site puts on-screen smoking in true light

American Pharmaceutical Partners - Data presented on high-dose weekly Abraxane

American Society of Breast Surgeons - Better quality of life reported after sentinel node biopsy

Amgen, Inc. - Biotech company names Willard Dere senior VP, global development

AngioDynamics, Inc. - EvenMore chronic hemodialysis catheter launched

Anthem Blue Cross and Blue Shield - Health insurance company launches more robust Web site

Apeliotus Technologies - Grant will aid effort to build new diagnostic device

Attenuon, LLC - Pharmaceutical company names Steven D. Reich chief medical officer

Austrian Breast and Colorectal Cancer Study Group - Zoledronic acid prevents bone loss in hormone-treated breast cancer patients

B-Bridge International - DiscoveRx, partner to provide screening assays to Japanese markets

Baker Heart Research Institute, Melbourne - Partitioning of AT1 signals permits separation of short-term AngII actions

Baskent University - High cholesterol levels weaken breast cancer metastasis

Bausch & Lomb - U.S. FDA approves vision-correction treatment to correct nearsightedness

Baylor College of Medicine, Houston - Ginseng has potential benefits on the CV system through diverse mechanisms

Baywood International, Inc. - EpiPharma securities begin trading on Pink Sheets

Bio-Matrix Scientific Group Inc. - Storage Suites America changes name, announces 1-10 reverse stock split

BioTech Medics, Inc. - Reverse merger completed with HaloLaser Biotherapy

Bioanalytical Systems, Inc. - Device maker reports 13% increase in revenue

Bioheart, Inc. - Trial data on stem cell treatment of heart failure presented

Breast Cancer - Model of growth may help psychosocial treatment in breast cancer survivors

Bright Now! Dental, Inc. - Dental company opens fifth office in Dallas/Ft. Worth, Texas, area

CISCRP Opinion Dynamics - Study shows most Americans think that clinical research studies are safe

California Pacific Medical Center, San Francisco - Structural mimicry in receptor rotamer toggle switches revealed

Carleton University, Ottawa - Proteins are targets for treatments to enhance cytoprotection of organ explants

Catalyst Pharmaceutical Partners - IND application filed for CPP-109 to treat cocaine addiction

CeMines, Inc. - Life sciences company creates international division

Cedara Software Corp - New software aids in breast ultrasound

Cell Genesys, Inc. - Encouraging data reported from phase II trial of leukemia vaccine

Center Hospital Intercommunal, Creteil - Effective varicella vaccine developed

ChemDiv, Inc. - Entercel, partner enter agricultural hit-to-lead identification program

Children's Hospital of Los Angeles - Mitochondrial DNA sequence variants point to migraine headache complications

Chinese Academy of Sciences - Porous interface designed for on-line CE-based separation system

Chinese University of Hong Kong - PPAR-alpha required for maintaining triacylglycerol homeostasis

ChondroGene, Ltd. - Companies ink new osteoarthritis collaboration

Dong-A University College of Medicine, Pusan - Vasopressin-induced genes in aquaporin-transfected MDCK cells identified

Duke University - Vaginal cuff scar excision is effective for primary and secondary repair

Dynavax Technologies - Interim analysis from ragweed allergy phase II/III trial announced

East Carolina University - Plasma fatty acid oxidation impaired in extremely obese women

Eastern Virginia Medical School - Proinflammatory potential of microbicide candidates assessed

Eberhard-Karls University Tubingen - Intramyocellular lipid increase during prolonged fasting investigated

Edwards Lifesciences Corp. - Prima Plus stentless porcine tissue heart valve approved in Japan

Eli Lilly and Company - J. Michael Cook elected to board of directors

Emergisoft - Hospital implements emergency department information system

Entegris, Inc. - Materials integrity management company reports multimillion dollar order

EpiVax, Inc - Protein and genome analysis company awarded grant to develop smallpox vaccine

Erciyes University, Seoul - Femoral geometry compared among older women with and without hip fracture

Exact Sciences - DNA test for colon cancer disappoints

Franek Technologies, Inc. - Company expands facilities to meet demand for laboratory power protection

Frost & Sullivan - Report on Cox-2 inhibitors indicates proof of safety difficult but crucial

GNC - Nutritional supplement company launches 'Total Lean Challenge' to help dieters

GeneWorks - Company launches Maui microarray hybridization system

Global Dosimetry Solutions, Inc. - Sander Perle, VP of dosimetry company, elected to CIRMS executive committee

Good Samaritan Hospital, Cincinnati - Study finds low prevalence of accompanying paravaginal defects

Griffith University, Southport - Selenium-deficient pregnant rats could serve as research model

Hana Biosciences, Inc. - Timothy J. Kinsella, MD, joins bioscience company's scientific advisory board

Harris Interactive - Poll reveals flu shot data

Harvard University - MRI recognizes stem cells bearing magnetic particles in murine hearts

Healthcare Coverage - Colorado Democrats float healthcare plan

Helicon Therapeutics, Inc. - Company begins phase I human testing of lead drug candidate HT-0712

Hokkaido University - Caspase-3 activation directly revealed in single live cells

Hokkaido University, Japan - Researchers report on association of H. pylori and gastric cancer

Humboldt University, Berlin - Electron beam tomograph is not suitable as a whole-body CT scanner

Icoria, Inc. - Biotechnology company granted 180 day minimum bid price extension by Nasdaq

Imperial College London - Genetics of APM1 locus contributes to type 2 diabetes susceptibility

Indiana University - Autologous platelet gels could expedite wound healing

Inex Pharmaceuticals Corporation - Biopharmaceutical company names senior vice president, corporate development

Influenza - Three new flu cases reported in New Mexico

Influenza Vaccines - Indian Health Services gives New Mexico 10,000 flu vaccines

Infusia - Company strengthens position in central and eastern Europe

Institut Gustave-Roussy, Villejuif - Anesthesia for cervicofacial cancer surgery reviewed

Institut de Biologie de Lille - Transmembrane domains of yellow fever virus proteins are localization signals

Institute for OneWorld Health - $42.6M grant to fund antimalarial drug development

IntelliClaim - Healthcare claims company announces selection by four health plans

International Agcy Research Cancer, France - Researchers report on role of isothiocyanates in cancer prevention

Intl. Assoc. for Dental Research - Medical journal revamps: New editor, new content, new look, new access

Introgen Therapeutics - New clinical data for Advexin shows promise

Ion Health - New managed healthcare plan begins to enroll members

Japan Hokkaido Institute Public Health - Deer are reservoir of GUD+ Shiga toxin-producing E. coli 0157:H7 in Japan

Johns Hopkins Medical Institute - Bacteriolytic therapy generates immune response against experimental tumors

Johns Hopkins University, Baltimore - Targeted blockade of xanthine oxidase impacts postischemic cardiomyopathy

Joint Genome Institute - Chromosome 16 publication fulfills DOE's human genome commitment

KV Pharmaceutical Co. - KV adopts financial accounting board's EITF 04-8 ruling

Kanazawa Medical University - Blood pressure indexes compared in Japanese population

King's College London - King's opens center for age-related diseases research

Kuopio University of Hospital - Candidemia is rare in allogeneic stem cell transplantation recipients

Kyoto Prefectural University of Medicine - Growth hormone increases uncoupling protein mRNA levels in obese mice

Kyushu University - Akt may have key role in anti-apoptotic effect of estrogen in endothelial cells

Kyushu University - Coronary flow response to bradykinin is preserved by ACE inhibitors in aged mice

Lebanese University - Method developed to produce antibodies specific for MSP-3 protein in mice

Leiden/Amsterdam Center for Drug Research - Utility of capillary isoelectric focusing-mass spectrometry evaluated

Lexicon Genetics, Inc. - United States Army awards biodefense grant

M.D. Anderson Cancer Center - Cytokeratin 7 and EMA help differentiate ovarian yolk sac tumors

MWW Group - Public relations agency selected by health centers for lobbying activities

Magellan Health Services, Inc. - Behavioral health company provides 2005 financial guidance

March of Dimes - Smallest surviving baby introduced, need to prevent premature births underscored

Massachusetts Institute of Technology - Cartilage-like tissue engineered with mesenchymal SCs and silk protein scaffolds

Maxim Pharmaceuticals - Investigational new drug application filed for pro-apoptotic cancer candidate

Mayne Group Limited - Development and supply agreement signed for injectable, non-cytotoxic products

Mayo Clinic - Simple fingertip test may reveal early coronary disease

McKesson Health Solutions, LLC - Health Hero Network included in Medicare Chronic Care Improvement Program

Medical College of Georgia - Endoscopic sinus surgery is safe, effective in older patients

Memorial Sloan-Kettering Cancer Center - Chemotherapy useful for liver metastases from colorectal cancer

Memorial University of Newfoundland - Anticore antibody signals occult woodchuck hepatitis virus infection

Memory, Pharmaceuticals Corp. - Pharma company appoints new board member

Meningitis - Law requires colleges to provide meningitis information

Michigan State University - Urotensin-II analyzed, physiological effect revealed in aortic adventitia

Milliman - White paper offers insight on funding of long-term care

MiraiBio Inc. - Information technology company launches new solution

Montefiore Medical Center, New York - Sputum assessment in firefighters exposed to World Trade Center dust reported

MorphoSys AG - Drug discovery company announces partnership with Schering AG

Mt. Sinai School of Medicine, New York - Initiation of haemangioblast in primitive streak of mouse embryo revealed

NPS Pharmaceuticals, Inc. - Pharma company completes private placement with institutional investors

NPS, Pharmaceuticals, Inc. - Pharma company names new board members

NW University - Vitamin supplementation benefits cardiovascular system of healthy males

Nabi Biopharmaceuticals - Biopharma company submits marketing authorization for StaphVAX

Nagoya University - Novel microtubule-associated protein identified in mice

Nantes University Hospital - Hematopoietic differentiation can lead to human herpesvirus 6 reactivation

National Autonomous University of Mexico - N-glycosylated growth hormone isoform characterized in chickens

National Cancer Center Research Institute, Tokyo - Dendritic cell vaccine has antitumor effect against pancreatic cancer

National Council on the Aging - Aging organization applauds creation of The Hearing Health Network

National Def Med College -  Mycoplasma pneumoniae and chlamydia may be important cofactors for CAD

National Taiwan University - Disseminated HPV-11 infection in patient with pemphigus vulgaris reported

Niigata Cancer Hospital - Human leukocyte antigen-A24-restricted antitumor cell generated

Norrland University Hospital, Sweden - Conduction disturbance is associated with increased repolarization inhomogeneity

Northwestern University - Neuronal HCN channels linked to synchrony development

Novartis - Cancer drug patent sparks Indian legal battle

Novartis Pharmaceuticals Corp. - U.S. FDA approves Enablex for treatment of overactive bladdter

NuVasive, Inc. - Medical device company announces management changes

Nycomed - Wound healing product manufacturing agreement signed

Oak Ridge National Laboratory - Genomic heat shock response of Shewanella oneidensis characterized

Ohio State University - API-59CJ-OMe may possess therapeutic potential for some endometrial cancers

Ono Pharmaceutical Co. - Colitis studied, role of neutrophil elastase inhibitor revealed

Oregon Health & Science University - Researcher says U.S. FDA could broaden access to results of clinical drug trials

Osaka University - Exportin 1 export studied, role of alternative splicing of Staufen2 revealed

PRAECIS PHARMACEUTICALS INCORPORATED - Pharma company announced draft decision for National coverage of Abarelix

Partnership for Safe Medicines - Association for importing medicine hires former FDA official

Peak 10 - Clinical trial-focused data management company picks services provider

Peninsula Medical School - Hepatocyte nuclear factor-4 alpha P2 promoter variants linked to diabetes

Pennsylvania Office of Attorney General - Pennsylvania funds Medicad fraud control section through settlement

Pfizer Ltd. - Murine multiple drug resistance 1a gene deficiency produces colitis symptoms

PhytoCeutica, Inc. - Doctors say herbal blend can help cancer patients

Prostate Cancer - Effect of evidence-based education package evaluated in prostate cancer patients

Quest Diagnostics Incorporated - Diagnostics company calls for redemption of contingent convertible debentures

Rikshospitalet University Hospital - Mucosal immune system reviewed

Russian Academy of Science, Chernogolovka - HIV-1 double-helix destabilization near cleaved bond promotes 3'-end processing

Scripps Research Institute - Hydrogen-bonded encapsulation complexes in protic solvents characterized

Seoul National University - Alpha-synuclein analyzed, similarities to small heat shock proteins revealed

Serologicals Corporation - Biological products provider announces closing of public offering

Shionogi & Co. Ltd. - Cardioprotective effects of drugs may deteriorate in hypertrophied hearts

Sidney Kimmel Cancer Center - Adenoviral vector vaccine process to overcome anergy to antigens described

Smith & Nephew, Inc. - Medical device co. receives FDA approval for ceramic-on-ceramic hip replacement

Stanford University - New universal linkers identify and amplify nucleic acid signals

State University of Rio de Janeiro - Malnourishment during lactation causes lack of anorexia after leptin

Sygen International, plc - Genaissance Pharmaceuticals signs research agreement

Taichung Vet. General Hospital, Taipei - Budding defect of HIV matrix mutants reversed with additional 107-matrix codons

TeamStaff, Inc. - Healthcare services company announces Q4 and fiscal year 2004 financial results

Tel Aviv Sourasky Medical Center - Anisotropic water diffusion in white matter characterized

Theratechnologies - Company gets $12 million for Macroflux projects, requests U.S. FDA meeting

ThyroTec, Inc. - New U.S. FDA-approved test detects thyroid disease in minutes

Toho University, Tokyo - Cutting balloon angioplasty is best for treating small coronary lesions

Tohoku University - Immortalized dendritic cell line with cross-priming ability developed

Tokyo Medical & Dental University - SNT-2 interaction with ERK2 studied, negatively regulation revealed

Tokyo Medical University - Toremifene provides better profiles of lipid metabolism compared to tamoxifen

Tokyo University of Agriculture - Serum uric acid and urea nitrogen suppressed by dietary fiber

Tokyo Women's Medical University - Ultrafine carbon black particles cause proliferation of human airway epithelium

TriZetto - Software companies join forces to enable provider contracting for health plans

Trinity Broadcasting Network - Religious broadcaster challenges Missouri churches to 'Get Fit'

U.S. Centers for Disease Control & Prevention - Web- versus paper-based surveys of gay and bisexual men compared

U.S. Health and Human Services - Teen drug use declines 2003-2004, concerns remain about inhalants, painkillers

U.S. National Institute of Health - L-carnitine and acetyl-L-carnitine promising for HIV-related complications

U.S. National Institutes of Health - Novel system allows site/subunit-specific unnatural AA incorporation into HIV-RT

UCB Pharma, Inc. - Pharma company submits applications for antiepileptic and intravenous Keppra

UN Integrated Regional Information Networks - In Gabon, illegal abortions cause one in four pregnancy-related deaths

Univ. Federal de Minas Gerais, Belo Horizonte - Roles of activin and inhibin in the human breast studied

Univ. of California, Los Angeles - Postnatal exposure to leptin causes altered adult female phenotype

Univ. of California, Los Angeles - Yellow pigment in curry spice blocks, breaks up brain plaques in mice

Univ. of California, Santa Barbara - National Science Foundation picks UCSB for center for materials research

Univ. of Texas, San Antonio - Exercise timing affects lipemia in hypertriglyceridemic men

University Clinic, Aachen - Review reports use of S-100 protein in monitoring acute neurological diseases

University College London - Sudden death from stress linked to wonky signals in the brain

University Klinikum Essen - Transcription factor Gfi1 regulates self-renewal and engraftment of HSCs

University Medical Center Erlangen - Highly selective adenoviruses show specificity for melanoma cells

University Medicine Berlin -  Chlamydophila pneumoniae activity can lead to heart disease

University at Buffalo - Scientists achieve nonviral gene delivery in vitro and track it in real-time

University of Arkansas - Staphylococcal thermostability studied, nuclease residue packing implicated

University of Athens - Novel Bayesian method reconstructs known HIV-1CRF04_cpx transmission network

University of Barcelona - Rat whole blood pyrogen test may provide alternative to rabbit testing

University of Basel Hospital - Diagnosis of vertebral osteomyelitis from non-TB mycobacteria is challenging

University of Birmingham - Tumor necrosis factor or insulin affects sulfotransferase activity in colon

University of Bologna - A newly identified mtDNA transition causes Leber's hereditary optic neuropathy

University of British Columbia - FSHR overexpression activates oncogenic pathways in surface epithelial cells

University of California, Davis - Lymphoid and nonlymphoid organs under continuous immunosurveillance

University of Central Venezuela - Outcomes of hypogonadism in women with chronic kidney disease assessed

University of Geneva - Cellular sources of new pancreatic beta cells reviewed

University of Georgia, Athens - Genes identified that are enriched in embryonic stem cells

University of Glasgow - Long walks before eating may blunt harm of fatty meals

University of Illinois, Urbana - Loss of cyclin-dependent kinase inhibitors produces obesity

University of Illinois, Urbana-Champaign - Microfluidic device enables

University of Kansas - Nuclear pore conformation studied, role of ryanodine receptors revealed

University of Leipzig - P2 purinoceptors modulate accumbal extracellular glutamate levels

University of Liege - Specific NF-kappaB inhibition in lungs: Potential pulmonary-allergy therapy?

University of London - Identification of cadmium exposure as risk factor may help reduce incidence

University of Louisville - 6-Phosphofructo-2-kinase expression reduces insulin sensitivity

University of Michigan - Convection microfluidic systems facilitate DNA analysis

University of North Carolina - Americans not guarding well enough against injurious, deadly falls

University of Oxford - Abnormal Nodal-Pitx2c pathway is a unifying mechanism for CV malformations

University of Paris - NF-kappaB/c-Jun LTR binding in G2 -arrested cells required for CBP recruitment

University of Paris, Le Kremlin-Bicetre - Impact of acromegaly treatment on long-term survival is questionable

University of Pennsylvania, Philadelphia - Vesicouterine fistula can resolve spontaneously with only conservative care

University of Pittsburgh - Role of c-Fes tyrosine kinase in hematopoietic and neuronal cells clarified

University of Quebec - Novel estrogen-platinum(II) hybrid molecules evaluated vs. gynecologic cancers

University of Sao Paulo - Activation of the sympathetic drive is responsible for hypertensive response

University of Schleswig-Holstein - Recombinant BMP-7 superior to platelet-rich plasma in sinus grafting

University of Sydney - Complete or partial resolution of PV stenosis occurs in one third of cases

University of Tampere - Physical workload has more wearing effects than training effects on workers

University of Tennessee - Leukocyte-derived myeloperoxidase amplifies endothelial dysfunction

University of Texas School of Medicine, Houston - Memory for contextual fear suppressed by entorhinal cortex plasticity

University of Tokyo - Study results indicate activation of c-Met in gastric carcinoma tissue

University of Toronto - Nonverbal cues often signal child abuse

University of Toronto - Pregnancy is possible after uterine artery embolization of fibroids

University of Tubingen - Labor, ovariectomy effect neuronal changes influencing continence in rats

University of Ulsan - Pancreatic islets isolated in porcine pancreas with new enzyme

University of Uppsala - Type-specific associations of HPV load with cancer risk needs more study

University of Utah - Dietary supplement use among chronically ill children

University of Vermont - The buzz on caffeine

University of Western Australia, Crawley - Functional luteolysis in pregnant rabbit CL correlates with apoptotic activity

University of Western Ontario - QT heart rate and T wave variability are greater during sudden intense exercise

University of Wisconsin - Race, community disadvantage, and BMI among U.S. adults analyzed

University of Wurzburg - Findings reveal evidence for cardiomyopathy in patients with DM2/PROMM

University of Zurich Hospital - CpG oligodeoxynucleotides block HIV-1 replication in lymphoid tissue

University of Zurich Hospital - Foam cell formation in atherogenesis studied, kinase requirement revealed

Utah State University - Phosphatases inhibited by phosphotyrosine analogue and related phosphonic acids

VHA, Inc. - Survey shows hospital infection control staff spread too thin

VNUS Medical Technologies, Inc. - Study: Closure procedure provides superior patient benefits

Valley Forge Scientific Corp. - Electrosurgical systems company reports fiscal 2004 and Q4 operating results

Vanderbilt University - Ascorbic acid recycling impaired by high glucose metabolism in beta cells

Veterinary Medicine - Drug company sent warning letter for tardy reporting of animal drug deaths

ViOptix - Medical device company names Debra Young vice president, chief financial officer

Vicuron Pharmaceuticals - Pharmaceutical company submits NDA for antibiotic to treat skin infections

Vilnius State University - Echovirus 13 outbreak presented as viral meningitis in Lithuanian children

Vodafone - "Confident" living for people with special needs

Wake Forest University - Patient protection laws don't favor health providers

Wake Forest University, Winston Salem - Obese older women with condition have higher lean mass, visceral fat, sTNFR1

Washington University - Mice with depression-like behaviors reveal possible source of human depression

Washington University, St. Louis - Appearance alone is insufficient to diagnose velocardiofacial syndrome

Weill Cornell Medical Center - Fast-acting vaccine starts working in mice within hours

Weizmann Institute of Science - Extracellular signal-regulated kinase studied, novel properties demonstrated

WellChoice, Inc. - Insurance company finalizes rates for New York City contract extension

XOMA Ltd. - Robert S. Tenerowicz named vice president by biopharmaceutical company

Xcyte Therapies, Inc. - Results of 2 clinical trials of T cells in multiple myeloma presented

YM BioSciences Inc. - Bioscience company reports positive EGF-R antibody pivotal phase 2 results

Yale University - BM-derived cells contribute to epithelial engraftment during wound healing

Yonsei University - Peritubular capillary C4d not linked to chronic rejection

Yonsei University, Seoul - Estrogen receptor and p53 levels may factor into SUI development

York University, Toronto - Mechanism of Nodal's protective effects elucidated in vitro

deCODE genetics - Phase 2 clinical trial of gene decoding drug for asthma announced

drugstore.com, inc. - Online drugstore names Kathy Gersch chief marketing officer, GM and VP

eGene Inc. - U.S. Patent issued for optical genomic testing, channel detection

eResearchTechnology, Inc. - Pharmaceutical company awards $1.4 million for cardiac study support services

sanofi-aventis - Pharma company receives notice of allowance for Lovenox patent

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