Vanderbilt University
PI3-kinase pathway involved in early progression
Published in Lab Business Week, January 30th, 2005
"Signaling through the phosphatidylinositol 3-kinase (PI3-kinase) pathway has been associated with lung tumorigenesis," scientists in Tennessee explained.
In a recent study, P.P. Massion and coauthors at Vanderbilt University "examined the association between gene copy number of the PI3-kinase catalytic subunit alpha (PIK3CA) and phosphorylated Akt expression in invasive and preinvasive lung cancers."
"We sought to determine at what stage of tumor development gene copy number increase or phosphorylated Akt overexpression might affect tumor...
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Source: Lab Business Week (2005-01-30)
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