Keio University,Tokyo
Neurotrophic factor protects SOD1 toxicity in amyotrophic lateral sclerosis
Published in Lab Business Week, February 6th, 2005
"ALS is the most common fatal motor neuron disease, affecting mostly middle-aged people. There are no curative therapies for ALS. Several lines of evidence have supported the notion that the proapoptotic property of familial ALS (FALS)-linked mutant Cu/Zn -superoxide dismutase-1 (SOD1) genes may play an important role in the pathogenesis of some FALS cases.
"Here," reported T. Chiba and colleagues, "we found that activity-dependent neurotrophic factor (ADNF), a...
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Source: Lab Business Week (2005-02-06)
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